FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Cisto pericárdico gigante: relato de caso Giant pericardial cyst: case report
Brazilian Journal of Cardiovascular Surgery, 2007 Os cistos pericárdicos são anomalias congênitas incomuns, sendo a maioria assintomática e diagnosticadas incidentalmente na radiografia de tórax. Os cistos gigantes são raros, havendo poucos relatos concernentes à sua história natural, apresentação ...
Vinicius José da Silva Nina +3 more
doaj +1 more source
Long-Term Radial Artery Grafts with Previous Midterm Proven Patency
Brazilian Journal of Cardiovascular Surgery, 2023 Introduction: Left internal thoracic artery to left anterior descending artery (LITA-LADA) grafting has become a fundamental part of coronary artery bypass grafting (CABG).
Roberto Rocha e Silva +3 more
doaj +1 more source
Surgical Strategies and Results for Repair of Pulmonary Atresia with Ventricular Septal Defect and Major Aortopulmonary Collaterals: Experience of a Single Tertiary Center [PDF]
Brazilian Journal of Cardiovascular Surgery, 2020 Objective: To evaluate surgical management and results of patients with pulmonary atresia and ventricular septal defect with major aortopulmonary collateral arteries (PA/VSD/MAPCAs).
Sertac Haydin +6 more
doaj +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The role of relaxin in the regulation of human liver and kidney fibrosis [PDF]
, 2009 Liver fibrosis has a range of aetiologies and is a global cause of mortality. Acritical effect of liver fibrosis which also increases mortality is portalhypertension.
Hayden, Annette Louise
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Renal ischemia and transplantation predispose to vascular constriction mediated by angiotensin II type 1 receptor-activating antibodies [PDF]
, 2012 BACKGROUND: We previously described angiotensin II type 1 receptor-activating antibodies (AT1R-Abs) in renal transplant recipients with vascular rejection and malignant hypertension.
Batuman, V. +15 more
core +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
OBSERVATIONS ON THE PATHOLOGICAL CHANGES FOLLOWING EXPERIMENTAL HYPERTENSION PRODUCED BY CONSTRICTION OF THE RENAL ARTERY [PDF]
Journal of Experimental Medicine, 1938 The clinical histories and pathological findings of six animals dying within a few days following bilateral constriction of the renal arteries have been presented. No explanation for the rise in blood pressure was found. The clinical histories and pathological findings of twelve animals with a sustained hypertension have been considered ...
openaire +2 more sources