Results 161 to 170 of about 19,523 (194)

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

open access: yesChemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang   +8 more
wiley   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

open access: yesChemistry &Biodiversity, Accepted Article.
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali   +11 more
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Closure of a Late‐Onset Iatrogenic Left Ventricular Pseudoaneurysm Caused by Erosion of an Apical Muscular VSD Device

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We report the case of a 3‐year‐old asymptomatic girl (12 kg, 96 cm) who was diagnosed with a large iatrogenic left ventricular pseudoaneurysm (LVP) on follow‐up ultrasound, 14 months after apical muscular ventricular septal defect (VSD) closure with a 10 mm Amplatzer Muscular VSD occluder (Abbott, USA) due to device erosion.
Raymond N. Haddad   +3 more
wiley   +1 more source

Novel Transthoracic Pulmonary Valve Implantation Using Self‐Expanding Salus Valve: A Prospective Study of Safety and Mid‐Term Outcomes

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter pulmonary valve replacement (TPVR) has emerged as a valuable treatment for severe pulmonary regurgitation (PR). The Salus valve (Balance Medical Technology Co. Ltd., Beijing, China) represents a novel self‐expanding valve stent designed for deployment through a transthoracic approach with a small subxiphoid incision ...
Ziqin Zhou   +6 more
wiley   +1 more source

The Impact of Underlying Plaque Characteristics Following the Third‐Generation Resorbable Magnesium Scaffold Implantation: An Intravascular OCT Assessment up to 12‐Months

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Third‐generation resorbable magnesium scaffold (RMS) was developed with stronger mechanical properties and thinner struts compared to its predecessor. This study aimed to assess the influence of the OCT‐derived underlying plaque characteristics on in‐scaffold late lumen loss (LLL) in patients treated with RMS up to 12‐months ...
Alp Aytekin   +9 more
wiley   +1 more source

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