Results 171 to 180 of about 21,873 (292)

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

Advanced Science, EarlyView.
The self‐trapped excitons in carbon quantum dots can serve as NIR‐II absorbers, which efficiently induce pyroptosis by driving the generation of reactive oxygen species through mild NIR‐II photothermal effect. Combined with local photophysical therapy and the cascade reaction of pyroptosis, it can activate systemic immunity and prevent tumor recurrence.
Tesen Zhang, Qingcheng Wang, Quansheng Cheng, Han Wang, He Feng, Hui Zhang, Mengbo Lin, Feili Cai, Zheng Fang, Ruo Wang, Gang Chen   +10 more
wiley   +1 more source

Aberrant Right Subclavian Artery With a Bicarotid Trunk: A Rare Cause of Stridor in Infants. [PDF]

Clin Case Rep
Alashqar M, Salman I, Saadeh S, Lubbadeh S, Khasati O.   +4 more
europepmc   +1 more source

CD169+ Macrophage‐Targeted Immunomodulator to Restore Phagocytic Function and Enhance Antigen Presentation for Lymphatic Metastasis Eradication

Advanced Science, EarlyView.
A CD169+ macrophage‐targeted immunomodulator (G‐LNP@S‐D) is developed to co‐deliver a SHP2 inhibitor and STING agonist, thereby restoring phagocytic function, enhancing antigen presentation by CD169+ macrophages, and promoting T cell priming to eradicate lymphatic metastasis.
Xiayun Chen, Lichong Lu, Yibin Liu, Ziqi Liang, Jianqiao Li, Zhouchuan Shao, Youzhi Tang, Jianhua Zou, Shiying Li, Xiaoyuan Chen   +9 more
wiley   +1 more source

Inhibition of Scarb1 on Endothelial Cells Attenuates Pressure Overload-Induced Heart Failure Progression. [PDF]

JACC Basic Transl Sci
Katsuki T, Kusumoto D, Akiba Y, Kimura M, Komuro J, Nakamura T, Hashimoto H, Kouka T, Sugai K, Katsumata Y, Miyasaka M, Suzuki Y, Kuramoto J, Kubota Y, Fukuda K, Yuasa S, Ieda M.   +16 more
europepmc   +1 more source

HAMPAO-SPECT of the brain and ocular microangiopathic syndrome in patients infected with the human immunodeficiency virus type 1 [PDF]

, 1993
Bogner, Johannes R., Einhäupl, Karl Max, Geier, Stephan A., Goebel, Frank-Detlef, Hammel, Gertrud, Sadri, Ifna, Schielke, Eva, Tatsch, Klaus   +7 more
core  

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Robotic Bilateral Ileal Interposition: The Total Intracorporeal Approach. [PDF]

Int Braz J Urol
Yee CH, Ko IC, Tam HM, Wong HF, Lo KL, Chan WH, Liu AQ, Teoh JY, Chiu PK, Ng CF.   +9 more
europepmc   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source

Burden and characteristics of inherited retinal diseases in China. [PDF]

Sci Rep
Lin Y, Dou X, Li L, Zhou W, Zhang W, Wang L, Wang JZ, Shen Y.   +7 more
europepmc   +1 more source

Washington University Medical Alumni Quarterly, July 1941 [PDF]

, 1941

core   +1 more source