Results 41 to 50 of about 21,873 (292)

Cisto pericárdico gigante: relato de caso Giant pericardial cyst: case report

Brazilian Journal of Cardiovascular Surgery, 2007
Os cistos pericárdicos são anomalias congênitas incomuns, sendo a maioria assintomática e diagnosticadas incidentalmente na radiografia de tórax. Os cistos gigantes são raros, havendo poucos relatos concernentes à sua história natural, apresentação ...
Vinicius José da Silva Nina, Norman Colina Eduardo Manzano, Vinícius Giuliano Gonçalves Mendes, Natalino Salgado Filho   +3 more
doaj   +1 more source

HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease. [PDF]

, 2015
Fructose is a major component of dietary sugar and its overconsumption exacerbates key pathological features of metabolic syndrome. The central fructose-metabolising enzyme is ketohexokinase (KHK), which exists in two isoforms: KHK-A and KHK-C, generated
A Casonato, A Corrionero, A Hirschy, A Troilo, A Ventura, Alexandre Sarre, Ana Vukolic, AR Grosso, C Wang, CA Lewis, CJ David, CP Diggle, CP Diggle, Cédric Cortijo, Fiona Grimm, GL Semenza, GW Yip, H Dolatshad, H Kuroda, I Falcão-Pires, I Shiojima, J Fukuzawa, J Krishnan, J Krishnan, J König, J Rappsilber, JA Haefliger, JA Hill, Jaya Krishnan, Jernej Ule, JM Buescher, K-Y Kim, L van Heerebeek, LE Huang, M Fang, M Nemir, M Shiota, Manuel Hörl, Melis Kayikci, MG Vander Heiden, MG Vander Heiden, N-H Son, Nicola Zamboni, Niklaus Fankhauser, NL Barbosa-Morais, NS Radin, Owen Feehan, P Cirillo, Peter Mirtschink, R Koopman, R Ramasamy, S Bonnal, S Sharma, Samuel Sossalla, Sebastian N. Stehr, T Fuhrer, T Ishimoto, T Kawasaki, Thierry Pedrazzini, W Luo, WG Kaelin, Wilhelm Krek, Y Gao, Yann Christinat, Z Kassiri   +64 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]

, 2016
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed, Al-Abed, Yousef, Coleman, Thomas, Lakshminrusimha, Satyanarayana, Patel, Hardik, VanPatten, Sonya   +5 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

The Impediment of Impotency and the Condition of Male Impotence: A Canonical-Medical Study: Medical Considerations [PDF]

, 1959
To present the problems involved in the matter of male impotence as related to the validity of marriage, the canonical considerations, as prepared by Rev. Paul v.
Harrington, Paul V., Kickham, Charles J.E.   +1 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Traumatic arterial thoracic outlet syndrome after multiple rib fractures not including the first rib in Korea: a case report [PDF]

Journal of Trauma and Injury
Arterial thoracic outlet syndrome (TOS) resulting from thoracic trauma is an exceedingly rare condition, typically caused by a fracture of the first rib or clavicle.
Seock Yeol Lee
doaj   +1 more source

Preductal Segmental Tubular Aortic Hypoplasia in Perinatally Died Stabyhoun Puppies

Animals, 2023
Background: A high perinatal mortality rate in the Stabyhoun breed prompted one of the Dutch breeding organizations to start an investigation. Preductal segmental tubular aortic hypoplasia is an extremely rarely documented congenital vascular anomaly in ...
Marie D. B. van Staveren, Guy C. M. Grinwis, Marjolein L. den Toom, Viktor Szatmári   +3 more
doaj   +1 more source

Stroke and migraine is there a possible comorbidity? [PDF]

, 2016
The association between migraine and stroke is still a dilemma for neurologists. Migraine is associated with an increased stroke risk and it is considered an independent risk factor for ischaemic stroke in a particular subgroup of patients.
Del Balzo, Francesca, Duse, Marzia, Nicita, Francesco, Occasi, Francesca, Papetti, Laura, Properzi, Enrico, Spalice, Alberto, Zicari, Anna Maria   +7 more
core   +2 more sources