Results 41 to 50 of about 19,523 (194)

Diagnostic and Therapeutic Approach in Intestinal Tuberculosis [PDF]

, 2016
Tuberculosis was still a global health problem. Beside lung, tuberculosis also manifest in other organs, one among them is in abdominal organs. Abdominal tuberculosis was a complex disease with unspecific sign and symptoms so that its diagnostic ...
Guno, T. H. (Tri), Kamelia, T. (Telly), Makmun, D. (Dadang), Putra, B. A. (Barry)   +3 more
core   +1 more source

Myocardial Protective Effect of Tezosentan, an Endothelin Receptor Antagonist, for Ischemia-Reperfusion Injury in Experimental Heart Failure Models [PDF]

, 2009
The myocardial protective effects of endothelin antagonist in ischemic cardiomyopathy (ICMP), doxorubicin-induced cardiomyopathy (DOX) and pressure-overload hypertrophy by transverse aortic constriction (TAC) models have been predicted to be different ...
Arai, Arnolda, Arola, Battistini, Bauch, Cernacek, Cheng, Duchman, Fishman, Gomez-Garre, Hansen, Hark Jei Kim, Hayashi, Heineke, Houser, Inada, Kaddoura, Kyu Ran Cho, Lako-Futo, Margulies, McMurdo, Nguyen, Nguyen, Olson, Omland, Parker, Richard, Sakai, Se Min Ryu, Sirvio, Teerlink, Teerlink, Watanabe, Webb, Wei, Wittner, Won-Min Jo, Xia, Yorikane   +38 more
core   +2 more sources

Intelligent Eye Tracker Integrated with Cylindrical Capacitive Sensors for Chronic Fatigue Assessment

Advanced Sensor Research, EarlyView.
A wearable capacitive eye tracker for chronic fatigue assessment is presented, utilizing cylindrically shaped capacitive sensors made of a carbon nanotube‐paper composite. By integrating a novel fatigue‐induction protocol with machine learning, the device achieves 0.75‐sensitivity and 0.73‐specificity, providing a practical alternative to existing ...
Tianyi Li, Seo‐Hyun Park, Changwoo Lee, Shawn Kim, Younghoon Kwon, Hojun Kim, Jae‐Hyun Chung   +6 more
wiley   +1 more source

Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure. [PDF]

, 2018
Heart failure (HF) is characterized by abnormal mitochondrial calcium (Ca2+) handling, energy failure and impaired mitophagy resulting in contractile dysfunction and myocyte death.
Bers, Donald M, Daugherty, Daniel J, Dedkova, Elena N, Deng, Wenbin, Frederich, Bert J, Lu, Xiyuan, Schaefer, Saul, Thai, Phung N   +7 more
core   +2 more sources

Non‐Invasive Diagnosis of Hypertrophic Cardiomyopathy by Breath

Advanced Sensor Research, EarlyView.
The use of sensor technologies for the diagnosis of hypertrophic cardiomyopathy (HCM) by identification of volatile organic compounds (VOCs) in breath samples. By combining gas chromatography‐mass spectrometry (GC‐MS) and electronic nose (eNose) platforms, specific VOC patterns associated with HCM are detected and analyzed.
Yael Hershkovitz‐Pollak, Manhal Habib, Yoav Y. Broza, Olga Katz, Harry Rakowski, Hossam Haick   +5 more
wiley   +1 more source

Upconversion‐Based Remote Deep Brain Modulation for Therapeutic Dissection of Parkinson's Disease

Advanced Therapeutics, EarlyView.
An upconversion‐based wireless optogenetic strategy enables an all‐optical deep brain modulation solution for treating Parkinson's disease in rodent animals without using electronics or any tethered cables, providing experimental evidence supporting a therapeutic mechanism of STN‐DBS by disruption of anterograde signal transmission along the indirect ...
Wenchong Zhang, Xudong Lin, Kai Xie, Zixun Wang, Tianying Sun, Zhen Xu, Haibing Yue, Xi Chen, Qinghai Liao, Ming Liu, Wing Ho Yung, Jufang He, Feng Wang, Peng Shi   +13 more
wiley   +1 more source

Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature [PDF]

, 2012
ObjectivePatients with severe left ventricular pressure overload secondary to aortic stenosis can present with signs and symptoms of heart failure despite normal left ventricular ejection fraction.
Dixon, Jennifer A., Eckhouse, Shaina R., Ikonomidis, John S., Mukherjee, Rupak, Oelsen, J. Marshall, Rivers, William T., Spinale, Francis G., Stroud, Robert E., Yarbrough, William M., Zile, Michael R.   +9 more
core   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer's disease [PDF]

, 2019
BACKGROUND: Melanopsin-expressing retinal ganglion cells (mRGCs), intrinsically photosensitive RGCs, mediate the light-based pupil response and the light entrainment of the body's circadian rhythms through their connection to the pretectal nucleus and ...
Oh AJ, Amore G, Sultan W, Asanad S, Park JC, Romagnoli M, La Morgia C, Karanjia R, Harrington MG, Sadun AA.
core   +1 more source