Results 51 to 60 of about 272,721 (287)

Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]

, 2020
Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib, Kempa, Stefan, Langer, Henning Tim, Spuler, Simone   +3 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Capsaicin-Induced Ca2+ Influx and Constriction of the Middle Meningeal Artery [PDF]

, 2014
Research in the past on transient receptor potential cation channel subfamily V member 1 (TRPV1) has been limited to mainly nervous tissue TRPV1 because of the channel’s role in pain perception.
Koide, Masayo, Kotlikoff, Michael I., Manuelyan, Inessa, Shui, Bo, Syed, Arsalan U., Wellman, George C.   +5 more
core   +1 more source

Pinning and depinning of a classic quasi-one-dimensional Wigner crystal in the presence of a constriction

, 2005
We studied the dynamics of a quasi-one-dimensional chain-like system of charged particles at low temperature, interacting through a screened Coulomb potential in the presence of a local constriction.
A. I. Larkin, A. Pertsinidis, D. S. Fisher, F. M. Peeters, G. Piacente, M. C. Hellerqvist, P. B. Littlewood, P. Drude, R. Kubo   +8 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Bilateral popliteal entrapment syndrome in a young athlete diagnosed with ultrasound

Radiology Case Reports, 2022
Popliteal artery entrapment syndrome (PAES) occurs when the popliteal artery is compressed by abnormally developed or hypertrophied muscles adjacent to the popliteal fossa.
Hanna K. Thompson, BS, Justin R. Montgomery, MD, Paul J. Spicer, MD   +2 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Acoustoelectric effects in quantum constrictions

, 1997
A dc current induced in a quantum constriction by a traveling acoustic wave (or by non-equilibrium ballistic phonons) is considered. We show that in many important situations the effect is originated from acoustically-induced scattering between the ...
A. Esslinger, A. Grincwajg, A. J. Kent, A. J. Naylor, A. Knäbchen, A. L. Efros, A. Wixforth, A. Wixforth, D. J. McKitterick, Frank A. Maaø, Frank A. Maaø, G. R. Nash, H. Karl, H. Totland, J. M. Shilton, J. M. Shilton, J. M. Shilton, L. I. Glazman, L. J. Challis, M. Blencowe, M. Büttiker, R. L. Willett, R. Landauer, Supriyo Datta, V. L. Gurevich, V. L. Gurevich, Y. Galperin   +26 more
core   +1 more source

Constricted channel flow with different cross-section shapes [PDF]

, 2017
Pressure driven steady flow through a uniform circular channel containing a constricted portion is a common problem considering physiological flows such as underlying human speech sound production. The influence of the constriction’s cross-section shape (
Gao, H., Luo, X.Y., Van Hirtum, A., Wu, B.   +3 more
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source