Results 51 to 60 of about 268,047 (306)

Tuberculous constrictive pericarditis [PDF]

open access: yesResearch in Cardiovascular Medicine, 2015
Constrictive pericarditis is characterized by constriction of the heart secondary to pericardial inflammation. Cardiovascular magnetic resonance (CMR) imaging is useful imaging modality for addressing the challenges of confirming this diagnosis. It can be used to exclude other causes of right heart failure, such as pulmonary hypertension or myocardial ...
Tse, Gary   +5 more
openaire   +5 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Control of Andreev bound state population and related charge-imbalance effect

open access: yes, 2014
Motivated by recent experimental research, we study the processes in an ac driven superconducting constriction whereby one quasiparticle is promoted to the delocalized states outside the superconducting gap.
Houzet, Manuel   +3 more
core   +3 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

“Hot Septum” Sign of Constrictive Pericarditis

open access: yesJACC: Case Reports, 2020
In patients with constrictive pericarditis, a characteristic reduction in the regional longitudinal strain seen in the areas of the left ventricular free wall and relative sparing of the septal longitudinal strain values create an easily recognizable ...
Edgar Argulian, MD MPH   +1 more
doaj   +1 more source

Resonant tunneling through protected quantum dots at phosphorene edges

open access: yes, 2016
We theoretically investigate phosphorene zigzag nanorribons as a platform for constriction engineering. In the presence of a constriction at the upper edge, quantum confinement of edge protected states reveals resonant tunnelling Breit-Wigner ...
Bahamon, D. A.   +3 more
core   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Controlling hysteresis in superconducting constrictions with a resistive shunt

open access: yes, 2015
We demonstrate control of the thermal hysteresis in superconducting constrictions by adding a resistive shunt. In order to prevent thermal relaxation oscillations, the shunt resistor is placed in close vicinity of the constriction, making the inductive ...
Biswas, Sourav   +4 more
core   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Magnetic domain walls in constrained geometries

open access: yes, 2004
Magnetic domain walls have been studied in micrometer-sized Fe20Ni80 elements containing geometrical constrictions by spin-polarized scanning electron microscopy and numerical simulations. By controlling the constriction dimensions, the wall width can be
A. Bischof   +5 more
core   +1 more source

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