Results 91 to 100 of about 1,395,438 (305)

Nonparametric Inference via Bootstrapping the Debiased Estimator

, 2019
In this paper, we propose to construct confidence bands by bootstrapping the debiased kernel density estimator (for density estimation) and the debiased local polynomial regression estimator (for regression analysis).
Chen, Yen-Chi, Cheng, Gang
core   +1 more source

Testing and comparing two self-care-related instruments among older Chinese adults [PDF]

, 2017
Objectives The study aimed to test and compare the reliability and validity, including sensitivity and specificity of the two self-care-related instruments, the Self-care Ability Scale for the Elderly (SASE), and the Appraisal of Self-care Agency Scale ...
A Millar, AL Comfrey, BF Damásio, BY Kearney, CL Wong, D. L. Streiner, Daniel Serrani Azcurra, DE Orem, EJ Pedhazur, GC Evers, GX Zeng, H Gao, H Gao, Han Gao, HH Wang, JA Zauszniewski, Jacqueline McCallum, JC Nunally, JW Osborne, JZ Shi, K Sundsli, Kun Liu, L Guo, L Guo, L Robinson, Lina Guo, LN Guo, M Lorensen, M Lorensen, M Zhou, MH Almeida, MS Fok, O Söderhamn, O Söderhamn, O Söderhamn, O Söderhamn, O Söderhamn, Qiyun Guo, RW Brislin, ST Tomstad, ST Tomstad, T van Achterberg, Ulrika Söderhamn, VD Sousa, X Wang, X Wang, XG Wang, Xianfei Ding, Yanjin Liu, YL Gao, ZS Nasreddine   +50 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Psychometric Properties of the Arabic Version of the Depressive Cognition Scale in First-Year Adolescent Egyptian Nursing Students [PDF]

, 2010
Background: Identifying depressive cognitions in adolescent nursing students can be an important step to prevent the development of clinical depression, which is positively associated with suicide.
Bekhet, Abir K., Zauszniewski, Jaclene
core   +2 more sources

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Validation of a high‐fidelity simulator for diagnostic knee arthroscopy training

Journal of Experimental Orthopaedics
Purpose To validate a high‐fidelity arthroscopic simulator by assessing its construct, face and content validity for diagnostic knee arthroscopy training.
Oliver Tze Rong Lim, Jeremy Tze En Lim, Jingyan Fang, Dileepa Banagala, Samundeeswari Saseendar, Salim A. L. Habsi, James Hui, Yee Han Dave Lee, Ying Ren Mok   +8 more
doaj   +1 more source

Validation of the Thai version of the family reported outcome measure (FROM-16)© to assess the impact of disease on the partner or family members of patients with cancer [PDF]

, 2019
© The Author(s). 2019Background: Cancer not only impairs a patient's physical and psychosocial functional behaviour, but also contributes to negative impact on family members' health related quality of life.
Areewan Cheawchanwattana, Aumkhae Sookprasert, B Edwards, CJ Golics, CJ Golics, HF Kaiser, JFTR Hair, JM Ramada-Rodilla, JW Lim, JW Vardiman, KE Covinsky, Kosin Wirasorn, LJ Cronbach, M Koller, M Tavakol, ME Varnum, MM Mukaka, N Friethriksdottir, Nutjaree Pratheepawanit Johns, Pattariya Chantarasap, PM Watcharee Leurmarnkul, R Mahendran, R Mahrer-Imhof, RB Cattell, S Mahatnirunkul, S Wood-Dauphinee, Sam Salek, SH Kim, Srivieng Pairojkul, Suphat Subongkot, W Meecharoen   +30 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Bitara Values Inventory

Asian Journal of Assessment in Teaching and Learning, 2012
This paper reports on a study in which an inventory was developed to measure the extent to which the academic staff of a university upheld the shared values of the university.
Ahmad Jazimin Jusoh, Othman Lebar, Mohd Nasir Bistamam, Syed Sofian Syed Salim, Mohamad Aziz Shah Mohamad Arip, Taqudin Abdul Mukti, Napisah Kepol, Samsiah Mohd Jais, Rasyidi Johan   +8 more
doaj