Results 81 to 90 of about 1,395,438 (305)
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Assessing the construct validity of aberrant salience
We sought to validate the psychometric properties of a recently developed paradigm that aims to measure salience attribution processes proposed to contribute to positive psychotic symptoms, the Salience Attribution Test (SAT).
Kristin Schmidt, Jonathan P Roiser
doaj +1 more source
Hōmai te Waiora ki Ahau: te ara whakamua - towards the establishment of construct validity [PDF]
Hōmai te Waiora ki Ahau: te ara whakamua, is about the development of a tool to measure psychological wellbeing among Māori. Why is it relevant? Because a quick look at the June 2002 edition of New Zealand’s Journal of Psychology will show you that
Palmer, Stephanie
core +1 more source
Measuring religious social capital: the scale properties of the Williams Religious Social Capital Index (WRSCI) among cathedral congregations [PDF]
The theoretical construct of social capital remains contested in terms of conceptualisation and measurement. The present paper follows the convention of distinguishing between trust, bonding, bridging and linking social capital, to conceptualise how ...
Williams, Emyr
core +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Dimensionality and Construct Validity of the Romanian Self-Report Strengths and Difficulties Questionnaire (SDQ) [PDF]
The Strengths and Difficulties Questionnaire (SDQ) is one of the most widely utilised measures of behavioural and emotional difficulties among children and young people.
Asiminei, Romeo +4 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Erin G Mistretta,1,2 Danetta Sloan,1 Karlynn BrintzenhofeSzoc,3 Kathleen M Weber,4 Ann Berger1 1Pain and Palliative Care Service, National Institutes of Health, Bethesda, MD, 2Department of Psychology, Catholic University of America, Washington, DC ...
Mistretta EG +4 more
doaj
An assessment of the construct validity of environmental strategy measures [PDF]
The natural resource-based view of the company is emerging as a dominant paradigm for understanding the intersection of strategic management and the natural environment.
Berrone, Pascual +2 more
core

