Results 111 to 120 of about 5,766,560 (402)
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno+12 more
wiley +1 more source
An examination of the construct validity of the Generalized Pliance Questionnaire [PDF]
The Generalized Pliance Questionnaire (GPQ) was originally validated against measures of psychological flexibility and psychological distress. However, measures which have substantial conceptual overlap with the GPQ (e.g., the Need to Belong Scale [NTBS],
Beekman+29 more
core +1 more source
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
Most autophagic cell death studies lack evidence of causality
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
An assessment of the construct validity of environmental strategy measures [PDF]
The natural resource-based view of the company is emerging as a dominant paradigm for understanding the intersection of strategic management and the natural environment.
Berrone, Pascual+2 more
core
Understanding Hope: A Review of Measurement and Construct Validity Research [PDF]
Hope has been discussed by philosophers, theologians, educators, and scientists, to name but a few groups of people, over the preceding two millennia. During the last 15 years, C. R.
Edwards, Lisa+3 more
core +1 more source
Nonparametric Inference via Bootstrapping the Debiased Estimator
In this paper, we propose to construct confidence bands by bootstrapping the debiased kernel density estimator (for density estimation) and the debiased local polynomial regression estimator (for regression analysis).
Chen, Yen-Chi, Cheng, Gang
core +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior+5 more
wiley +1 more source
Examining validity in computerized dynamic assessment
Computerized dynamic assessment (CDA) posits itself as a new type of assessment that includes mediation in the assessment process. Proponents of dynamic assessment (DA) in general and CDA in particular argue that the goals of DA are in congruence with ...
Alonazi Zaha
doaj +1 more source
A Critical Evaluation of Selective Attention Measures [PDF]
Selective attention is comprised of two simultaneous processes—the inhibition of distractors and the focus of attention on target stimuli; yet, many existing selective attention measures only measure one aspect of selective attention.
Wilson, Hannah K.
core +1 more source