Results 31 to 40 of about 9,281,684 (290)

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld   +5 more
wiley   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

DEFINITION OF TIME: FROM THE SECOND TO CONSTRUCTAL LAW [PDF]

open access: yes
One of the open problems in Physics is the analytical definition of time. This paper addresses a possible answer to this topic by proposing an analytical definition of time obtained by the Second Law of Thermodynamics and the Constructal Law ...
Grisolia, G., Lucia, U.
core   +1 more source

Constructal design applied to the optimization of heat transfer in a solid conducting wall

open access: yesVetor, 2010
The present paper applies Constructal Design to optimize the geometry of a Yshaped negative fin that intrudes a solid conducting wall with heat generation. The main goal is the minimization of the thermal global resistance between the solid wall and the
Crístofer Hood Marques   +2 more
doaj   +4 more sources

Constructal Optimizations of Liquid-Cooled Channels with Triangle or Square Sections in a Cylindrical Heating Body

open access: yesMathematics, 2023
Two new integrated models with heat source–heat sink are established, in which isothermal liquid cooling channels with triangle or square sections are, respectively, embedded in a cylindrical heating body with uniform heat production.
Yunfeng Li   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Geometric optimization of complex thermal-fluid dynamic system by means of constructal design [PDF]

open access: yes, 2022
In this work the Constructal Theory is exposed in its generality, trying to approach it through examples mostly of a physical-engineering nature. Constructal Theory proposes to see living bodies as elements subject to constraints, which are built with a ...
Impiombato, Andrea Natale <1990>
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Constructal Design and Friction Stir Processing Synergy: Towards Next-Generation High-Efficiency Heat Sinks

open access: yesApplied Sciences
The continuous increase in electronic power densities demands thermal management solutions that surpass the conventional heat sink designs. This study introduces a synergistic approach that combines constructal design principles with Friction Stir ...
Joel de Jesus   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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