Results 41 to 50 of about 373 (250)

Constructive Methods of Program Design [PDF]

open access: yes, 1976
Correct programs cannot be obtained by attempts to test or to prove incorrect programs: the correctness of a program should be assured by the design procedure used to build it.
openaire   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

Numerical Study and Geometrical Investigation of an Onshore Overtopping Device Wave Energy Converter with a Seabed Coupled Structure

open access: yesJournal of Marine Science and Engineering, 2023
Studies regarding renewable energy sources have gained attention over recent years. One example is wave energy converters, which harvest energy from sea waves using different operational principles such as oscillating water columns, oscillating bodies ...
Andréia S. de Barros   +7 more
doaj   +1 more source

On the construction of handcuffed designs

open access: yesJournal of Combinatorial Theory, Series A, 1974
AbstractA handcuffed design with parameters ν, k, λ consists of a set of ordered k-subsets of a v-set, called handcuffed blocks; in a block (a1, a2, ak) each element is assumed to be “handcuffed” to its neighbors. A block, therefore, contains k − 1 handcuffed pairs, the pairs being considered unordered.
openaire   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Constructal theory of pattern formation [PDF]

open access: yesHydrology and Earth System Sciences, 2007
This review article shows that the occurrence of macroscopic flow configuration is a universal natural phenomenon that can be explained and predicted on the basis of a principle of physics (the constructal law): "For a flow system to persist in time
A. Bejan
doaj  

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Thermal optimization of circular bodies submitted to an intense heat flux using constructal design

open access: yesVetor, 2010
The present work studies the optimization of a circular body with an intense heat flux by Constructal Design. The problem concerns the minimization of the global thermal resistance of a three-dimensional structure submitted to an intense uniform heat ...
Leandro Cavalheiro Vergara   +2 more
doaj   +4 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Home - About - Disclaimer - Privacy