Results 61 to 70 of about 1,839 (290)

Modeling fluid dynamics and aerodynamics by second law and Bejan number (part 1 - theory) [PDF]

open access: yes, 2019
© 2019 Published by INCAS. Two fundamental questions are still open about the complex relation between fluid dynamics and thermodynamics. Is it possible (and convenient) to describe fluid dynamic in terms of second law based thermodynamic equations?
Pascoa, J, Trancossi, Michele
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Range-based techniques for discovering optimality and analyzing scaling relationships in neuromechanical systems [PDF]

open access: yes, 2009
In this paper, a method for decoupling the neuromuscular function of a set of limbs from the role morphology plays in regulating the performance of an activity is introduced.
Bradly J. Alicea
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A new paradigm for deep sustainability: biourbanism [PDF]

open access: yes, 2013
Biourbanism introduces new conceptual and planning models for a new kind of city, valuing social and economical regeneration of the built environment through developing and healthy communities.
Caperna, Antonio, Tracada, Eleni
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structure and adaptation of arteries to pulsatile flow - The case of the ascending aorta [PDF]

open access: yes, 2014
PURPOSE: The objectives are: (i) assess the development of the impedance of some arteries during the first decades of life; (ii) determine the influence of pulse rate in arterial impedance; (iii) compare the structure of some arterial segments with ...
Silva, Carla
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Novel design of a liquid-cooled heat sink for a high-performance processor based on constructal theory: A numerical and experimental approach

open access: yesAlexandria Engineering Journal, 2022
This study presented a novel liquid-cooled heat sink based on constructal theory. An experiment was conducted to investigate the influence of boundary conditions, such as the mass flow rate (ṁ), on heat transfer rate (Qin) and pressure drop.
Kittipong Sakamatapan   +6 more
doaj   +1 more source

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