Results 41 to 50 of about 302,712 (264)
CivilEngThis study aims to develop a reliable method for predicting power plant construction costs during the early planning stages using ensemble machine learning techniques.
Suha Falih Mahdi Alazawy +5 more
doaj +1 more source
Multiobjective optimization model for scheduling of construction projects under extreme weather
Journal of Civil Engineering and Management, 2016 Extreme weather significantly impacts construction schedules and costs and can be a source of schedule delays and budget overruns. A multi-objective optimization model, presented herein for the scheduling of construction projects under extreme weather ...
Ahmed B. Senouci, Saleh A. Mubarak
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Cost-Effective Thermal Mass Walls for Solar Greenhouses in Gobi Desert Regions
AgricultureGobi solar greenhouses (GSGs) enhance energy, food, and financial security in Gobi Desert regions through passive solar utilization. Thermal mass walls are critical for plant thermal comfort in GSGs but can lead to resource waste if poorly designed. This
Xiaodan Zhang +5 more
doaj +1 more source
Nuclear Power Learning and Deployment Rates; Disruption and Global Benefits Forgone
Energies, 2017 This paper presents evidence of the disruption of a transition from fossil fuels to nuclear power, and finds the benefits forgone as a consequence are substantial.
Peter A. Lang
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source