Results 51 to 60 of about 2,702,482 (307)

Mitigation measures for significant factors instigating cost overrun in highway projects [PDF]

, 2018
Construction industry has created numerous employment opportunities and playing a role model in economic growth of Pakistan. This industry is facing serious and critical problem of cost overrun especially in highway sector in country Pakistan ...
Abdullah, Abd Halid Bin, Ahmed Memon, Bashir, Kareem Bhatti, Nadeem Ul, Nagapan, Sasitharan, Sohu, Samiullah   +4 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Explainable Machine Learning to Predict the Construction Cost of Power Plant Based on Random Forest and Shapley Method

CivilEng
This study aims to develop a reliable method for predicting power plant construction costs during the early planning stages using ensemble machine learning techniques.
Suha Falih Mahdi Alazawy, Mohammed Ali Ahmed, Saja Hadi Raheem, Hamza Imran, Luís Filipe Almeida Bernardo, Hugo Alexandre Silva Pinto   +5 more
doaj   +1 more source

The project of sports complex with gyms, sports hall and swimming pool with the study of holding elements of structure [PDF]

, 2019
In master thesis project, the project of sports complex with gyms, sports hall and swimming pool with the study of holding elements of structure the main structural elements of the building were considered.
Салах, Шеріф Фавзі
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Mapping the e-business profile and trends in cost management in the UK construction industry [PDF]

, 2012
The advancement of e-business applications and IT infrastructure has had massive impact on construction business processes over the last decade. The added effects of globalisation coupled with global economic recession have forced businesses to implement
Park, Rachael, Perera, Srinath, Rodrigo, Anushi, Udeaja, Chika, Zhou, Lei   +4 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Cost-Effective Thermal Mass Walls for Solar Greenhouses in Gobi Desert Regions

Agriculture
Gobi solar greenhouses (GSGs) enhance energy, food, and financial security in Gobi Desert regions through passive solar utilization. Thermal mass walls are critical for plant thermal comfort in GSGs but can lead to resource waste if poorly designed. This
Xiaodan Zhang, Jianming Xie, Ning Ma, Youlin Chang, Jing Zhang, Jing Li   +5 more
doaj   +1 more source