Results 101 to 110 of about 2,280,486 (356)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Research on a Carbon Emission Prediction Model for the Construction Phase of Underground Space Engineering Based on Typical Resource Carbon Consumption and Its Application

open access: yesBuildings
The trend of global warming remains severe. As one of the major sources of carbon emissions, the construction industry still requires large-scale and effective transformations.
Yuan Mei, Haokun Wang, Dongbo Zhou
doaj   +1 more source

Research on construction technology of frame structure in construction engineering [PDF]

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract With the rapid development of the construction industry, the building technology needs to be improved day by day. The application of reinforced concrete frame structure is suitable for all kinds of projects for its strong seismic capacity, good integrity and durability.
openaire   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

For RWU Faculty, Key Role on Economic Development Research in Rhode Island [PDF]

open access: yes, 2013
Faculty members from economics, engineering and construction management leading cross-institutional research projects through statewide ...
Public Affairs, Roger Williams University
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Industry-driven innovative system development for the construction industry: The DIVERCITY project [PDF]

open access: yes, 2004
Collaborative working has become possible using the innovative integrated systems in construction as many activities are performed globally with stakeholders situated in various locations.
Aouad, GF, Arayici, Y
core  

Optimizing Construction Project Plan Management Using Parameter-Adaptive Improved Genetic Algorithm

open access: yesTehnički Vjesnik
This study proposes an optimization method for construction project plan management using a parameter-adaptive improved genetic algorithm (IGA) combined with differential evolution (DE).
Tianya Jia
doaj   +1 more source

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