The water supply of towns and the construction of waterworks. A practical treatise for the use of engineers and students of engineering. [PDF]
openalex +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
List of contents and message from the Responsible Director [PDF]
Message from the Responsible Director I am glad to announce publication of Volume 3, No.2 (2016) of Journal of “Structural and Construction Engineering”.
GholamReza Havaei
doaj
Early intervention mechanism for preventing electrocution in construction engineering. [PDF]
Shiau YR, Lo FY, Ko PC.
europepmc +1 more source
ENGINEERING CONFERENCE, 27TH MAY. SHIPBUILDING. IMPROVED MATERIALS OF CONSTRUCTION AND THEIR INFLUENCE ON DESIGN. (ABSTRACT). [PDF]
John H. Biles
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Rethinking IT in Construction and Engineering [PDF]
How could the potential of IT be realised to improve business performance in architecture, construction and engineering organisations? How could organisations unleash the potential of IT to achieve a sustainable competitive advantage? How can organisations migrate from technology to IT-enabled business thinking?
openaire +5 more sources
DISCUSSION. THE CONSTRUCTION OF PAVEMENTS ON CLAY FOUNDATION SOIL. ROAD ENGINEERING DIVISION. [PDF]
Renee Grigson+18 more
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source