Results 121 to 130 of about 2,425,065 (336)

Reform and Practice of the Course “Road Engineering Construction Technology and Organization” Based on Smart Classroom

, 2023
Li-Ming Zhao
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

List of contents and message from the Responsible Director [PDF]

Journal of Structural and Construction Engineering, 2016
Message from the Responsible Director     I am glad to announce publication of Volume 3, No.2 (2016) of Journal of “Structural and Construction Engineering”.
GholamReza Havaei
doaj  

On ADE Quiver Models and F-Theory Compactification

, 2005
Based on mirror symmetry, we discuss geometric engineering of N=1 ADE quiver models from F-theory compactifications on elliptic K3 surfaces fibered over certain four-dimensional base spaces.
A Belhaj, A Sebbar, Ait Ben Haddou M, Belhaj A, Belhaj A, Belhaj A, Belhaj A, Cachazo F Intriligator K Vafa C, Hori K Iqbal A Vafa C, Hori K Vafa C, J Rasmussen, Katz S, Landsteiner K, M B Sedra, Vafa C   +14 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Asserting the Portuguese Civil Engineering Identity: the Role Played by the École des ponts et chaussées [PDF]

, 2009
This paper focuses on the Portuguese engineers who returned to Portugal following a training period at École des Ponts et Chaussées, in Paris between 1831 and 1870.
Matos, Ana Cardoso de
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Analysis of Key Points of Steel Structure Construction Technology in Film Engineering Projects [PDF]

, 2023
M. Alashoub Turki Sulaiman, Chunyu Liang
openalex   +1 more source

SASICE: Safety and sustainability in civil engineering

, 2011
The performance of the built environment and the construction sector are of major importance in Europe’s long term goals of sustainable development in a changing climate. At the same time, the quality of life of all European citizens needs to be improved
Azevedo, J, Bloodworth, A., De Roeck, G, Esteban-Chapapria, V, Lobo, A, Lombaert, G, Magenes, G, Prinos, P, Savoia, M, Terti, G, Viggiani, G   +10 more
core  

SciTech News Volume 71, No. 3 (2017) [PDF]

, 2017
Columns and Reports From the Editor.........................3 Division News Science-Technology Division....5 Chemistry Division....................8 Conference Report, Marion E, Sparks Professional Development Award Recipient..9 Engineering Division......

core   +1 more source