Results 81 to 90 of about 2,428,776 (309)

(Anti)symmetric matter and superpotentials from IIB orientifolds

, 2003
We study the IIB engineering of N=1 gauge theories with unitary gauge group and matter in the adjoint and (anti)symmetric representations. We show that such theories can be obtained as Z2 orientifolds of Calabi-Yau A2 fibrations, and discuss the explicit
A. Giveon, A. Hanany, A. Klemm, B. Acharya, B. Acharya, C. Vafa, C.I. Lazaroiu, Calin Iuliu Lazaroiu, E. Witten, F. Cachazo, F. Cachazo, F. Cachazo, F. Cachazo, H. Fuji, H. Ita, I. Bena, I. Bena, I. Brunner, J.D. Edelstein, K. Dasgupta, K. Dasgupta, K. Dasgupta, K. Landsteiner, K. Landsteiner, K. Landsteiner, K. Landsteiner, K. Landsteiner, K. Landsteiner, K.-h. Oh, Karl Landsteiner, R. Dijkgraaf, R. Dijkgraaf, R. Dijkgraaf, R. Roiban, R.A. Janik, Radu Tatar, S. Elitzur, S. Sinha, S.G. Naculich, S.G. Naculich, S.K. Ashok, T.R. Taylor, V. Arnold   +42 more
core   +3 more sources

Large-scale Complex IT Systems [PDF]

, 2011
This paper explores the issues around the construction of large-scale complex systems which are built as 'systems of systems' and suggests that there are fundamental reasons, derived from the inherent complexity in these systems, why our current software
Antoniou G., Cabinet Office, Dave Cliff, Ian Sommerville, John Mcdermid, Justin Keen, Marta Kwiatkowska, Radu Calinescu, Richard Paige, Sillitto H.T., Tim Kelly, University of York.   +11 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Leveraging digital tools to advance mathematics competencies among construction students

Cogent Education
This study investigated the impact of integrating design-technological activities on developing mathematical competencies among construction engineering students. A mixed methods approach compared curriculum delivery with and without digital tools across
Elmira Saparbayeva, Marzhan Abdualiyeva, Yerlan Torebek, Nurlibay Madiyarov, Abay Tursynbayev   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Constructing living buildings: a review of relevant technologies for a novel application of biohybrid robotics [PDF]

, 2019
Biohybrid robotics takes an engineering approach to the expansion and exploitation of biological behaviours for application to automated tasks. Here, we identify the construction of living buildings and infrastructure as a high-potential application ...
Bar-Yam Y, Bonabeau E, Calkins M, Chaudhuri P, Ching FDK, Daas M, Daniel Nicolas Hofstadler, Danks SG, Ednie-Brown P, Elsayed S, Erlandson W, Gandy M, Gibaldi J, Gramazio F, Gunther N, Heiko Hamann, Hughes TJR, Joachim M, Johnson D, Jørgensen RN, Kalberer M, Kalberer M, Kasper Stoy, Katola K, Kirsch K, Ludwig F, Mary Katherine Heinrich, Mohammad Divband Soorati, Mostafa Wahby, Nagaraja H, Payam Zahadat, Phil Ayres, Proksch G, Pérez G, Rafał Krela, Rafiei MH, Reames R, Reames R, Russell S, Schaeffer J, Schmitz V, Schweitzer F, Sebastian von Mammen, Slavid R, Soorati MD, Thomas Schmickl, Thouand G, Tomasz Skrzypczak, Wahby M, Warnes J, Wojciech Kwiatkowski, Wooldridge M, Yu Y   +52 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Research on a Carbon Emission Prediction Model for the Construction Phase of Underground Space Engineering Based on Typical Resource Carbon Consumption and Its Application

Buildings
The trend of global warming remains severe. As one of the major sources of carbon emissions, the construction industry still requires large-scale and effective transformations.
Yuan Mei, Haokun Wang, Dongbo Zhou
doaj   +1 more source

SciTech News Volume 71, No. 2 (2017) [PDF]

, 2017
Columns and Reports From the Editor 3 Division News Science-Technology Division 5 Chemistry Division 8 Engineering Division 9 Aerospace Section of the Engineering Division 12 Architecture, Building Engineering, Construction and Design Section of the

core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source