Results 101 to 110 of about 2,007,738 (306)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

UK construction processes and IT adoptability: Learning form other industries [PDF]

open access: yes
Process improvement has been identified as a mechanism of achieving the desired performance improvements of the UK construction industry. During the recent past, researches within UK construction process improvement research paradigm have been influenced
Amaratunga, Dilanthi   +2 more
core  

Coping with lists in the ifcOWL ontology [PDF]

open access: yes, 2015
Over the past few years, several suggestions have been made of how to convert an EXPRESS schema into an OWL ontology. The conversion from EXPRESS to OWL is of particular use to architectural design and construction industry, because one of the key data ...
Beetz, Jakob   +3 more
core   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Pine wood nematode disease area identification based on multi-temporal multi-source remote sensing images and BIT model

open access: yesGeocarto International
Pine wood nematode (PWN) disease is a severe contagious disease in forests which endangers the health of forests, as it can rapidly kill trees. The detection of regions impacted by this disease plays a crucial role in forest management, remediation ...
Degao Wang   +6 more
doaj   +1 more source

Trade credit in the UK construction industry: an empirical analysis of construction contractor financial positioning and performance [PDF]

open access: yes, 2013
Research commissioned by the Department for Business, Innovation & Skills (BIS) to inform analysis for the ‘Industrial Strategy for Construction’. It explores the availability of trade credit for UK construction firms and how they rely upon it to support
Ive, G, Murray, A
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Microstructure-Driven Feasibility of Crushed Bamboo Coarse Aggregate for Structural–Insulating Wall Composites

open access: yesBuildings
This study evaluates crushed bamboo as a coarse aggregate for structural–thermal wall composites, comparing its performance against mixes with wood sawdust and rice husk.
Aliaksandr Bakatovich   +5 more
doaj   +1 more source

Are we catering to the construction industry KM requirements?: A literature synthesis [PDF]

open access: yes
The concept of Knowledge Management is now familiar to the construction industry and various attempts are being made for the effective management of knowledge in the industry.
Amaratunga, Dilanthi   +2 more
core  

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