Results 91 to 100 of about 5,734,746 (248)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Improving technology transfer in the Australian construction industry
, 2006 The construction industry is a significant component of the Australian economy. One of the features of this industry is that many of its member organisations are small and medium enterprises (SMEs).
Ryan, Neal, Thorpe, David
core +1 more source
Results in EngineeringAsphalt pavement in cold regions often suffer from serious cracking issues, which will greatly shorten its service life. Composite modification employing polyphosphoric acid (PPA), crumb rubber (CR), and styrene-butadiene-styrene block copolymer (SBS ...
Fucheng Guo +8 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Identifying suitable land for dust storm barriers in Al-Anbar region using GIS
Journal of Degraded and Mining Lands ManagementThis study employed an integrated Geographic Information System (GIS) and Analytic Hierarchy Process (AHP) methodology to identify optimal locations for sand and dust storm barriers in Iraq’s Al-Anbar Governorate.
Aseel M. Hussein +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Immersive learning behavior analysis based on UWB positioning and innovative education mode
Discover Applied SciencesThe rapid development of intelligent education and human-computer interaction has given rise to the demand for immersive learning, which has raised higher requirements for indoor spatial positioning accuracy and learning behavior recognition ability.
Xiangcui Huang +3 more
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
An in-depth analysis of e-procurement use in UK construction organisations [PDF]
, 2010 Eadie et al (2007) show that there are many advantages in the adoption of e-procurement within a construction organisation. However, its uptake within the construction industry has been inadequately researched.
Eadie, Robert +3 more
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