Results 91 to 100 of about 3,079,502 (307)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Mobile Paving System (MPS): A New Large Scale Freeform Fabrication Method [PDF]

, 2005
In the last decade, significant opportunities for automation have been identified in the area of construction. Soaring labor and material costs have driven multiple research efforts in construction automation.
Asiabanpour, B., Mata, J., Sriraman, V., Tseng, A., Um, D., Wahed, N.   +5 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Fire-resistant materials for aircraft passenger seat construction [PDF]

The thermal response characteristics of fabric and fabric-foam assemblies are described. The various aspects of the ignition behavior of contemporary aircraft passenger seat upholstery fabric materials relative to fabric materials made from thermally ...
Fewell, L. L., Kourtides, D. A., Moussa, A., Tesoro, G. C.   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Design and construction aspects of a geocomposite drainage system in a dam [PDF]

, 2012
The drainage system of a dam depends mainly of the available granular material founded near the dam site and it’s quantities. In some cases, the use of natural granular materials can reach an impracticable cost considering the transportation and the ...
Gerheim Souza Dias, Tiago, Vogt Volkmer, Mariana   +1 more
core   +1 more source

Micromorphological description of vernacular cob process and comparison with rammed earth [PDF]

, 2019
International audiencePast builders have developed very low-embodied energy construction techniques optimizing the use of local building materials. These techniques are a source of inspiration for modern sustainable building. Unfortunately, this know-how
Cammas, Cécilia, Cazacliu, Bogdan, Hamard, Erwan, Lemercier, Blandine, Morel, Jean Claude   +4 more
core   +5 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

DEVELOPMENT OF MATERIALS BUILDING MATERIALS ENVIRONMENTAL CONSTRUCTIVE-CONSTRUCTIVE SIDE

Jurnal Daya Matematis, 2013
The purpose of this research is to construct constructive, constructive, and effective construct-based constructive spacewalk construct materials, including Student Handbook, Student Activity Sheet (LKS), and Teacher Handbook. The existence of constructivist-based learning materials is expected to create a learning situation that allows students to ...
openaire   +1 more source

Materials and techniques of Art Nouveau architecture in Italy and Portugal: a first insight for an European route to consistent restoration [PDF]

, 2009
The results of the investigations on building materials and techniques of Casa Major Pessoa, a typical Art Nouveau construction in Aveiro (Portugal), and two coeval Art Nouveau buildings in Bologna (Italy) are presented as a methodological contribution
Dell’Acqua, A. C., Franzoni, E., Sandrolini, F., Varum, H.   +3 more
core   +1 more source