Results 61 to 70 of about 3,079,502 (307)

Design for sustainable architecture and environments [PDF]

open access: yes, 2008
This paper describes some of the research outcomes of a Knowledge Transfer Partnership (KTP) project partly funded by Department of Trade and Industry, UK.
Fieldson, Rosemary   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effect of steel fiber shape and content on printability, microstructure and mechanical properties of 3D printable high strength cementitious materials

open access: yesCase Studies in Construction Materials
This study investigates the effects of steel fiber shape (straight and hooked-end) and content (0, 0.5, 1.0, and 1.5 vol%) on rheological properties, printability, mechanical performance and microstructure of 3D printable steel fiber reinforced high ...
Zijian Jia   +7 more
doaj   +1 more source

Looking for Design in Materials Design

open access: yes, 2004
Despite great advances in computation, materials design is still science fiction. The construction of structure-property relations on the quantum scale will turn computational empiricism into true design.Comment: 3 pages, 1 ...
CS Smith   +5 more
core   +1 more source

Efficient construction of linear models in materials modeling and applications to force constant expansions [PDF]

open access: yes, 2020
Linear models, such as force constant (FC) and cluster expansions, play a key role in physics and materials science. While they can in principle be parametrized using regression and feature selection approaches, the convergence behavior of these ...
Erhart, Paul   +2 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Integrating continuous mineral-impregnated carbon fibers into digital fabrication with concrete

open access: yesMaterials & Design
Digital concrete technologies, such as 3D concrete printing, have the potential to be game changers in the construction industry by reducing material consumption and offering a high level of automation.
Tobias Neef   +2 more
doaj   +1 more source

A Sheep in Synthetic Wolf's Clothing: Creating a Hybrid of Natural and Man-Made Materials to Combine Protection and Aesthetics in a Cold Climate. [PDF]

open access: yes, 2013
For thousands of years, humans have experimented with methods of joining materials, not only to create objects for practical use but also to satisfy their desire for decoration and embellishment.
Kitchman, Fiona, Morehead, Sarah
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Soil micromorphology for construction science: the mortar archaeometry [PDF]

open access: yes, 2012
Micromorphology revealed in depth evaluation of materials particularly soil micromorphology yielded numerous data on processes such as formation, neoformation and transformation of minerals and microstructure in soils, pottery and construction materials.
Akça, Erhan   +3 more
core  

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