Results 101 to 110 of about 845,765 (317)

Adaption of structured analysis design techniques methodology for construction project planning

open access: yes, 2012
The construction industry has been heavily criticised by researchers and governmental organisations for its performance especially excessive delay. Ballard and Howell (2003) indicated that only about 50% of the tasks on weekly work plans are completed by
Pasquire, C   +2 more
core  

Fuzzy asymmetrical semi-quantitative project analysis in accordance with organizational strategy of risk management [PDF]

open access: yesمدیریت بهره وری, 2008
In recent years, risk management has become an inherent part of project management process, particularly in the large and complex projects.Various standards and procedures have been developed for its optimization.Because of short-comings in the ...
Mohammad Hassan Sobhieah   +2 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Construction project management in India

open access: yes, 2008
The Indian construction industry is known to be inefficient and highly resistant to change. Even with a changing market and increasing competition, there are no obvious signs of commensurate changes in methods and approach.
Skitmore, Martin, Auti, Atul
core  

A conceptual framework for multi-modal interactive virtual workspace [PDF]

open access: yes, 2001
Construction projects involve a large number of both direct stakeholders (clients, professional teams, contractors, etc.) and indirect stakeholders (local authorities, residents, workers, etc.).
Gobbetti, E   +13 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Sydney Opera House – FM exemplar project

open access: yes, 2005
The Sydney Opera House Facilities Management Exemplar Project (SOH FM Exemplar\ud Project) aims to develop innovative research on facility management (FM) with the focus on\ud asset maintenance.

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Is Agile Project Management Applicable to Construction?

open access: yes, 2006
This paper briefly summarises the evolution of Agile Project Management (APM) and differentiates it from lean and agile production and ‘leagile’ construction.
Owen, Robert   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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