Results 121 to 130 of about 845,765 (317)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Online Remote Construction Management\ud Part A: Construction Project Case Studies
, 2003 Computer application within construction companies began little more than a\ud decade after the first electronic computer was built (1950s). It seemed like a\ud promising start when breakthrough computer-based project management\ud techniques such as the
Weippert, Archim +2 more
core
Advancing Circular Buildings: A Review of Building Strategies for AEC Stakeholders
BuildingsThe uptake of a circular economy (CE) in the building sector is challenging, primarily due to the complexity associated with the design process and the dynamic interaction among architects, engineers, and construction (AEC) stakeholders. The standard and
Mohana Motiei +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Retracted: Value Proposition for Enabling Construction Project Innovation by Applying Building Information Modeling. [PDF]
Comput Intell Neurosci, 2023 Intelligence And Neuroscience C.
europepmc +1 more source
A constructive real projective plane
Journal of Geometry, 2015 The classical theory of plane projective geometry is examined constructively, using both synthetic and analytic methods. The topics include Desargues's Theorem, harmonic conjugates, projectivities, involutions, conics, Pascal's Theorem, poles and polars.
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Understanding project culture in construction : a literature synthesis
, 2012 Construction industry being a project-based industry, understanding nature of project culture is of paramount importance. Culture at project level seems less researched; possibly due to understanding of project culture seems a tedious task since it is ...
Samaraweera, Aparna +1 more
core
Evaluation and Improvement of Employee Performance with respect to Health, Safety, and Environment (HSE) Factors: A Case of Complex Transport Construction Project. [PDF]
Comput Intell Neurosci, 2023 Zhang X, Wang Y, Gao Y, Liu Y, Feng S.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source