Results 121 to 130 of about 847,107 (317)

Impact of Thrombolysis Time Metrics When Participating in National Stroke Center Construction Project. [PDF]

open access: yesJ Multidiscip Healthc, 2023
Cheng W   +13 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Report on the Development and Validation of the Best Practice Decision Matrix [PDF]

open access: yes, 2001
The Co-operative Research Centre for Construction Innovation (CRC-CI) is funding a project known as Value Alignment Process for Project Delivery. The project consists of a study of best practice project delivery and the development of a suite of products,

core  

Advancing Circular Buildings: A Review of Building Strategies for AEC Stakeholders

open access: yesBuildings
The uptake of a circular economy (CE) in the building sector is challenging, primarily due to the complexity associated with the design process and the dynamic interaction among architects, engineers, and construction (AEC) stakeholders. The standard and
Mohana Motiei   +3 more
doaj   +1 more source

A constructive real projective plane

open access: yesJournal of Geometry, 2015
The classical theory of plane projective geometry is examined constructively, using both synthetic and analytic methods. The topics include Desargues's Theorem, harmonic conjugates, projectivities, involutions, conics, Pascal's Theorem, poles and polars.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Generic skills in design teams [PDF]

open access: yes, 2005
Recent developments in networked three dimensional (3D) virtual worlds and the\ud proliferation of high bandwidth communications technology have the potential to\ud dramatically improve collaboration in the construction industry.\ud This research project

core  

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