Results 111 to 120 of about 845,765 (317)
Construction process categorisation towards developing an E-business maturity model
, 2014 The rapid pace of change in technology coupled with global economic and environmental changes has had considerable impact on all business sectors. Consequently, organisations are forced to drive towards efficiency savings, productivity improvements and ...
Zhou, Lei +4 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Mapping the e-business profile and trends in cost management in the UK construction industry
, 2012 The advancement of e-business applications and IT infrastructure has had massive impact on construction business processes over the last decade. The added effects of globalisation coupled with global economic recession have forced businesses to implement
Zhou, Lei +5 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Lean construction: Prospects for the German construction industry
, 2007 There is little, if any, information available about the range and dissemination of lean concepts among construction companies in Germany. Building on the methodologies and conceptual frameworks used in earlier work in the UK (Common et al., 2000) and ...
Walter, Lorenz, Johansen, Eric
core
Psychological contract expectations of construction project managers
, 2004 The past 20 years have seen a period of fundamental change for many construction businesses as they have restructured, downsized, de-layered, merged and de-merged to survive turbulent markets and rapidly changing demand cycles.
Dainty, ARJ, Neale, RH, Raidén, AB
core +1 more source
Constructions for projectively unique polytopes
Discrete Mathematics, 1976 AbstractA convex polytope P is projectively unique if every polytope combinatorially isomorphic to P is projectively equivalent to P. In this paper are described certain geometric constructions, which are also discussed in terms of Gale diagrams. These constructions are applied to obtain projectively unique polytopes from ones of lower dimension; in ...
openaire +2 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Surveying the extent and use of 4D BIM in the UK
, 2016 More than half of construction projects exceed their agreed time schedules. Attempts to remedy this have been monitored over a number of years in the UK using standard industry KPI measurement data.
Greenwood, David, Gledson, Barry
core
Impact of Thrombolysis Time Metrics When Participating in National Stroke Center Construction Project. [PDF]
J Multidiscip Healthc, 2023 Cheng W +13 more
europepmc +1 more source