Results 171 to 180 of about 4,661,284 (379)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Guideline for the Development of a Scenario-Based Senior Capstone Course for Construction Engineering and Management Students [PDF]
Namhun Lee, Seong Jin Kim, Jiyong Choi
openalex +1 more source
Virginity Control and Hymen (re)Construction: Gender Analysis from the Perspective of Young Women. [PDF]
Arch Sex BehavChristianson M, Eriksson C.
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Development of Conceptual Framework Influencing the Success of Collaboration among Organisation in Managing BIM Construction Project Based on Client Perspectives [PDF]
Raja Nor Husna Raja Mohd Noor +4 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
DISTRIBUTION CHANNELS OF MAJOR CONSTRUCTION MATERIALS
, 2015 Vesna Vučemilović
openalex +1 more source
La ligne ferroviaire Cahors-Capdenac, l’histoire de sa construction au regard de son inventaire [PDF]
Fabien Cadot, Guillaume Bernard
openalex +1 more source