Results 61 to 70 of about 3,573,253 (377)

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

open access: yesNew Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini   +9 more
wiley   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

An Examination of the Volitional Stages in Consumer Decisions to Avoid Sweatshop Clothing [PDF]

open access: yes, 2006
While much research in ethical consumption has focused on contexts such as food, this research explores ethical consumer decision-making in the context of intention to avoid sweatshop clothing where consumer concern has increased but response from the ...
Bekin, C   +5 more
core  

Consumer Behaviour in Retail: Next Logical Purchase using Deep Neural Network [PDF]

open access: yesarXiv, 2020
Predicting future consumer behaviour is one of the most challenging problems for large scale retail firms. Accurate prediction of consumer purchase pattern enables better inventory planning and efficient personalized marketing strategies. Optimal inventory planning helps minimise instances of Out-of-stock/ Excess Inventory and, smart Personalized ...
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

User-documented food consumption data from publicly available apps: an analysis of opportunities and challenges for nutrition research

open access: yesNutrition Journal, 2018
Background The need for a better understanding of food consumption behaviour within its behavioural context has sparked the interest of nutrition researchers for user-documented food consumption data collected outside the research context using publicly ...
Marcus Maringer   +8 more
doaj   +1 more source

Large UK retailers' initiatives to reduce consumers' emissions: a systematic assessment [PDF]

open access: yes, 2017
In the interest of climate change mitigation, policy makers, businesses and non-governmental organisations have devised initiatives designed to reduce in-use emissions whilst, at the same time, the number of energy-consuming products in homes, and ...
Abrahamse   +148 more
core   +1 more source

Empirically grounded agent-based policy evaluation of the adoption of sustainable lighting under the European Ecodesign Directive [PDF]

open access: yesAMPM'21: First Workshop in Agent-based Modeling & Policy-Making, December 8, 2021, Vilnius, Lithuania, 2022
Twelve years ago, the European Union began with the gradual phase-out of energy-inefficient incandescent light bulbs under the Ecodesign Directive. In this work, we implement an agent-based simulation to model the consumer behaviour in the EU lighting market with the goal to explain consumer behaviour and explore alternative policies.
arxiv  

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