Results 141 to 150 of about 45,474 (261)

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Strengthening health literacy research through consumer engagement: a qualitative analysis of building and maintaining partnership. [PDF]

Health Promot Int
Ayre J, Ferguson E, Taba M, Mac O, McFadden K, Tracy M, Edlund G, Ma ICK, Nadesan W, Yan J, Ng S, Slewa O, McCaffery KJ, Muscat DM.   +13 more
europepmc   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Neurocognitive Mechanisms Underlying Social Media Marketing and Purchase Intention: The Mediating Role of Consumer Engagement with Reference to Emotional Attention, and Cognitive Appraisal. [PDF]

Ann Neurosci
Bajpai M, Pandiya S, Mishra P, Agrawal PK, Kumar M.   +4 more
europepmc   +1 more source

Codesigning consumer engagement strategies with ethnic minority consumers in Australian cancer services: the CanEngage Project protocol. [PDF]

BMJ Open, 2021
Harrison R, Walton M, Manias E, Wilson C, Girgis A, Chin M, Leone D, Seale H, Smith AB, Chauhan A, CanEngage Project group.   +10 more
europepmc   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Mixed methods systematic review of consumer engagement in rural health practice, research, and education. [PDF]

Health Promot Int
Broadhurst T, Cha YJ, Bartlett C, Van Heerden J, Smith L, Lizarondo L, McGrail M, Nasir B, Hulme A, Kondalsamy-Chennakesavan S, Martin P.   +10 more
europepmc   +1 more source

Entropy Decoding the Fundamental Law of Phase Competition in Glass Formation

Advanced Science, EarlyView.
We validate the integration of intermetallic and eutectic phases as initial phases for composition design. The phase competition mechanism in glass formation is quantitatively clarified based on the melting entropy of competing phases. Glass‐forming ability is modulated by tuning phase competition via the melting entropy of initial phases.
Benke Huo, Zhengqing Cai, Bingtao Wang, Zhenqiang Song, Shi‐Dong Feng, Zijing Li, Xingjun Liu, Li‐Min Wang   +7 more
wiley   +1 more source

Consumer Engagement in the Design of Educational Nutrition Information for Older Adults and Their Caregivers: A Scoping Review. [PDF]

Adv Nutr
Lau A, Young AM, Han C, Miller EM, Heim ME, Miller MD.   +5 more
europepmc   +1 more source

Capsule Commentary on Castellon-Lopez et al.: "Psychometric Properties of the Altarum Consumer Engagement (ACE) Measure of Activation in Patients with Prediabetes". [PDF]

J Gen Intern Med, 2021
Palacio AM, Bast E.
europepmc   +1 more source