Results 41 to 50 of about 40,811 (265)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Organization of Preventive Vaccination against Dysentery under Conditions of Critical Emergencies Caused by Flood (Using the Example of Khabarovsk Territory)

Эпидемиология и вакцинопрофилактика, 2016
Aim: epidemiological zoning of the territory of Khabarovsk region that was conducted in accordance with levels of potential epidemic risk regarding dysentery in order to specify the priority of vaccination measures and non-specific prophylaxis of the ...
T. A. Zaitseva, O. E. Trotsenko, S. V. Balakhonov, Yu. A. Garbuz, T. V. Korita, A. P. Bondarenko, T. N. Karavyanskaya   +6 more
doaj   +1 more source

Prevalence of ARVI, influenza, and COVID-19 pathogens in individuals without symptoms of respiratory infection

Журнал микробиологии, эпидемиологии и иммунобиологии, 2021
Introduction. SARS-CoV-2 can be transmitted by infected people without or with mild symptoms of acute respira-tory infection (ARI). Monitoring based on nucleic acid amplification techniques is used to measure the prevalence of ARI pathogens and to assess
S. B. Yatsyshina, M. V. Mamoshina, M. A. Elkina, G. V. Sharukho, Yu. I. Raspopova, А. Ya. Folmer, K. A. Agapov, I. M. Vladimirov, O. V. Zubareva, I. S. Novikova, O. B. Bondareva, V. A. Gil, D. N. Kozlovskikh, S. V. Romanov, O. V. Dikonskaya, A. V. Ponomareva, I. V. Chistyakova, N. I. Kochneva, A. I. Yurovskikh, E. P. Kadnikova, A. S. Kilyachina, S. V. Luchinina, R. R. Kosareva, G. G. Chirkova, N. N. Valeullina, L. A. Lebedeva, T. N. Detkovskaya, E. I. Abbasova, O. B. Romanova, E. V. Pyatyrova, V. G. Akimkin   +30 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Pandemic influenza A/H1N1 (sw2009) in Russia: epidemiology, diagnosis, clinical picture, and treatment

Терапевтический архив, 2010
Aim. To study the epidemiological and clinical features of the 2009-2010 pandemic influenza in Russia. Subjects and methods. Materials from 874 patients, including postmortem samples from 287 subjects, were examined applying the AmpliSens Influenza virus
Svetlana Borisovna Yatsyshina, Andrey Nikolaevich Minenko, Tat'yanaya Evgen'evna Kushakova, Mariya Nikolaevna Praded, Anna Viktorovna Kudryavtseva, German Aleksandrovich Shipulin, Viktor Vasil'evich Maleev, V I Pokrovskiy, S B Yatsyshina, A N Minenko, T E Kushakova, M N Praded, A V Kudryavtseva, G A Shipulin, V V Maleyev, V I Pokrovsky   +15 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Antibiotic resistance and viral co-infection in children diagnosed with pneumonia caused by Mycoplasma pneumoniae admitted to Russian hospitals during October 2023—February 2024

BMC Infectious Diseases
Background Mycoplasma pneumoniae (MP) is a common bacterial respiratory infection that can cause pneumonia, particularly in children. Previously published data have highlighted the high incidence of viral co-infections and the problem of increasing ...
Elena Korneenko, Irina Rog, Ivan Chudinov, Aleksandra Lukina-Gronskaya, Anfisa Kozyreva, Ilmira Belyaletdinova, Julia Kuzmina, Oleg Fedorov, Daria Evsyutina, Alexey Shunaev, Daria Matyushkina, Vadim Govorun, Anna Speranskaya   +12 more
doaj   +1 more source

Acute diarrhea of bacterial etiology: differential diagnosis and treatment

Медицинский совет, 2016
The article tells about the main aspects of differential diagnosis and therapy for diarrheal syndrome. The main components of treatment and indications for antimicrobials in acute intestinal infections are considered.
T. A. Ruzhentsova, A. A. Ploskireva, A. V. Gorelov   +2 more
doaj   +1 more source

Studies of ticks of the genus Dermacentor (Acari; Ixodidae) on the natural occurrence of tularemia pathogen in the conditions of the Central Pre-Caucasian region

Российский паразитологический журнал, 2021
The purpose of the research is the assessment of the Francisella tularensis occurrence in nature in ticks of the genus Dermacentor; understanding the physiological age in terms of tick infection with tularemia pathogen.Materials and methods.
E. V. Lazarenko, O. A. Gnusareva, L. I. Shaposhnikova, V. M. Dubyansky   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source