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Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida [PDF]
PLoS ONE, 2016 Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s) behind ...
Karl Klose, Siva Sarva
exaly +2 more sources
PLoS Pathogens, 2009 Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis.
Anders Sjöstedt +2 more
exaly +3 more sources
Amoebae can promote the survival of Francisella species in the aquatic environment
Emerging Microbes and Infections, 2021 Francisella tularensis, a tier 1 select agent, is the causative bacterium of tularemia, a zoonosis with a large animal reservoir. However, F. tularensis, like many other Francisella species, is assumed to have an aquatic reservoir.
Aurélie Hennebique +8 more
doaj +1 more source
Microorganisms, 2023 Francisella tularensis is a zoonotic bacterium that is endemic in large parts of the world. It is absent in the standard library of the most applied matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) systems: the ...
Maaike C. de Vries +6 more
doaj +1 more source
Presence of Francisella tularensis subsp. holarctica DNA in the Aquatic Environment in France
Microorganisms, 2021 In 2018, the incidence of tularemia increased twofold in the west of France, with many pneumonic forms, suggesting environmental sources of infection. We investigated the presence of Francisellatularensis subsp.
Camille D. Brunet +5 more
doaj +1 more source
Nlrp3 Increases the Host’s Susceptibility to Tularemia
Frontiers in Microbiology, 2021 Francisella tularensis (F. tularensis) is a Gram-negative, intracellular bacterium and the causative agent of a fatal human disease known as tularemia. The CDC has classified F.
Ragavan V. Suresh +7 more
doaj +1 more source
Inguinal Ulceroglandular Tularemia Caused by Francisella tularensis Subspecies holarctica, Canada
Emerging Infectious Diseases, 2021 Tularemia is a zoonotic disease caused by the gram-negative coccobacillus Francisella tularensis, a Biosafety Level 3 pathogen and potential agent of bioterrorism.
Carl Boodman +6 more
doaj +1 more source
Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses. [PDF]
PLoS ONE, 2013 Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion that F.
Kathie-Anne Walters +8 more
doaj +1 more source
Francisella tularensis Subspecies holarctica and Tularemia in Germany
Microorganisms, 2020 Tularemia is a zoonotic disease caused by Francisella tularensis a small, pleomorphic, facultative intracellular bacterium. In Europe, infections in animals and humans are caused mainly by Francisella tularensis subspecies holarctica.
Sandra Appelt +5 more
doaj +1 more source
Early infection-induced natural antibody response
Scientific Reports, 2021 There remains to this day a great gap in understanding as to the role of B cells and their products—antibodies and cytokines—in mediating the protective response to Francisella tularensis, a Gram-negative coccobacillus belonging to the group of ...
Klara Kubelkova +4 more
doaj +1 more source