Francisella and Antibodies [PDF]
Immune responses to intracellular pathogens depend largely upon the activation of T helper type 1-dependent mechanisms. The contribution of B cells to establishing protective immunity has long been underestimated.
Klara Kubelkova, Ales Macela
doaj +4 more sources
Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida. [PDF]
Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s) behind ...
Siva T Sarva +3 more
doaj +5 more sources
In recent years, studies on the intracellular pathogen Francisella tularensis have greatly intensified, generating a wealth of new information on the interaction of this organism with the immune system. Here we review the basic elements of the innate and adaptive immune responses that contribute to protective immunity against Francisella species, with ...
Siobhan C Cowley, Karen L Elkins
exaly +5 more sources
Amoebae can promote the survival of Francisella species in the aquatic environment
Francisella tularensis, a tier 1 select agent, is the causative bacterium of tularemia, a zoonosis with a large animal reservoir. However, F. tularensis, like many other Francisella species, is assumed to have an aquatic reservoir.
Aurélie Hennebique +2 more
exaly +3 more sources
Molecular study of Francisella spp. from ticks in hedgehogs (Erinaceus europaeus) in urban-suburban areas of West Azerbaijan Province [PDF]
Wildlife plays a fundamental role in maintaining the complex balance of the ecology of tick-borne diseases, serving as both a host for ticks and a potential ecological role for the pathogens they carry.
Ahmad Enferadi +2 more
doaj +2 more sources
Tularemia in Çanakkale province, Marmara region, Turkey: a 10 years’ experience [PDF]
OBJECTIVE: In this retrospective study, we aimed to perform a clinical and laboratory evaluation of the cases of tularemia in the last 10 years in Çanakkale province, Marmara region, Turkey, which is considered an endemic area for the disease.
S. Alkan +3 more
doaj +1 more source
Francisella and tularemia in western Asia, Iran: a systematic review
Tularemia or rabbit fever is a transmissible disease from animals, rodents, and insects to human populations that is caused by Francisella tularensis. Epidemiological studies showed that tularemia is endemic throughout most different regions of the world.
Zahra Fooladfar, Farhad Moradi
doaj +1 more source
Comparative review of Francisella tularensis and Francisella novicida [PDF]
Francisella tularensis is the causative agent of the acute disease tularemia. Due to its extreme infectivity and ability to cause disease upon inhalation, F. tularensis has been classified as a biothreat agent. Two subspecies of F. tularensis, tularensis and holarctica, are responsible for tularemia in humans. In comparison, the closely related species
Kingry, Luke C., Petersen, Jeannine M.
openaire +2 more sources
Optimized MALDI TOF Mass Spectrometry Identification of Francisella tularensis Subsp. holarctica
Francisella tularensis is a tier 1 agent causing the zoonosis tularemia. This highly infectious Gram-negative bacterium is occasionally isolated from human samples (especially blood samples) in routine clinical microbiology laboratories.
Sofiane Regoui +5 more
doaj +1 more source
Genetic Determinants of Antibiotic Resistance in Francisella
Tularemia, caused by Francisella tularensis, is endemic to the northern hemisphere. This zoonotic organism has historically been developed into a biological weapon.
Stephen J. Kassinger +1 more
doaj +1 more source

