Frontiers in Microbiology, 2011 In recent years, studies on the intracellular pathogen Francisella tularensis have greatly intensified, generating a wealth of new information on the interaction of this organism with the immune system. Here we review the basic elements of the innate and adaptive immune responses that contribute to protective immunity against Francisella species, with ...
Cowley, Siobhán C., Elkins, Karen L.
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Comparative review of Francisella tularensis and Francisella novicida [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Francisella tularensis is the causative agent of the acute disease tularemia. Due to its extreme infectivity and ability to cause disease upon inhalation, F. tularensis has been classified as a biothreat agent. Two subspecies of F. tularensis, tularensis and holarctica, are responsible for tularemia in humans. In comparison, the closely related species
Kingry, Luke C., Petersen, Jeannine M.
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Reclassification of Francisella noatunensis subsp. orientalis Ottem et al. 2009 as Francisella orientalis sp. nov., Francisella noatunensis subsp. chilensis subsp. nov. and emended description of Francisella noatunensis [PDF]
, 2020 Francisella noatunensis is a fastidious facultative intracellular bacterial pathogen that causes ‘piscine francisellosis’, a serious disease affecting both marine and fresh water farmed and wild fish worldwide. Currently two F. noatunensis subspecies are
Richards, Randolph H +27 more
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Francisella tularensis pangenome
, 2023 Genomes of Francisella tularensis subspecies for pangenome analysis of the species. Genomes included:| Accession | Species | Strain || NC_006570 | Francisella tularensis subsp. tularensis | SCHU_S4 || NC_007880 | Francisella tularensis subsp. holarctica |
Genomica Microbiana (3901651) +1 more
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Studien zu Genominseln in und zur Virulenz von Francisella [PDF]
, 2019 Die genomische Insel (GI) FhaGI 1 des Stammes Francisella hispaniensis (Fhis) AS02 814 kann sowohl in die tRNAVal integriert als auch als episomale Form vorliegen und kodiert für einen putativen Prophagen. Im Rahmen dieser Arbeit konnte durch Verwendung
Tlapák, Hana
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Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A. [PDF]
PLoS ONE, 2016 Francisella tularensis, the Gram-negative bacterium that causes tularemia, produces a high molecular weight capsule that is immunologically distinct from Francisella lipopolysaccharide but contains the same O-antigen tetrasaccharide.
Jason H Barker +3 more
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Early infection-induced natural antibody response
Scientific Reports, 2021 There remains to this day a great gap in understanding as to the role of B cells and their products—antibodies and cytokines—in mediating the protective response to Francisella tularensis, a Gram-negative coccobacillus belonging to the group of ...
Klara Kubelkova +4 more
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Tularemia as a waterborne disease: a review
Emerging Microbes and Infections, 2019 Francisella tularensis is a Gram-negative, intracellular bacterium causing the zoonosis tularemia. This highly infectious microorganism is considered a potential biological threat agent.
Aurélie Hennebique +2 more
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Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses. [PDF]
PLoS ONE, 2013 Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion that F.
Kathie-Anne Walters +8 more
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Microbiology Spectrum, 2023 Francisella tularensis is a highly infectious Gram-negative bacterial pathogen capable of animal-to-human transmission. Due to its remarkable pathogenicity and potential for widespread public health impact, F.
Ashley Clarke +7 more
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