Results 11 to 20 of about 19,579 (213)
Francisella and Antibodies [PDF]
Immune responses to intracellular pathogens depend largely upon the activation of T helper type 1-dependent mechanisms. The contribution of B cells to establishing protective immunity has long been underestimated.
Klara Kubelkova, Ales Macela
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Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida. [PDF]
Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s) behind ...
Siva T Sarva +3 more
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First case of Francisella bacteraemia in Western Australia
Francisella species are Gram-negative, nonmotile, pleomorphic coccobacilli, facultative intracellular fastidious bacteria. We report the isolation of a Francisella-like species from a blood culture collected from a 44-year-old bacteraemic patient in ...
Max Aravena-Román +2 more
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Azithromycin effectiveness against intracellular infections of
Background Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum ...
Mann Barbara J +4 more
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The migratory behavior of wild birds contributes to the geographical spread of ticks and their microorganisms. In this study, we aimed to investigate the dispersal and co-occurrence of Francisella and spotted fever group Rickettsia (SFGR) in ticks ...
Tove Hoffman +23 more
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Although the study of pathogen sensing by host defense systems continues to uncover a role for inflammasome components specific to particular pathogens, gaps remain in our knowledge.
Srabani Mitra +4 more
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The Francisella intracellular life cycle: towards molecular mechanisms of intracellular survival and proliferation [PDF]
The tularemia-causing bacterium Francisella tularensis is a facultative intracellular organism with a complex intracellular lifecycle that ensures its survival and proliferation in a variety of mammalian cell types, including professional phagocytes ...
Audrey eChong, Jean eCelli
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The Francisella Type VI Secretion System
Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative agent of the life-threatening zoonotic disease tularemia.
Daniel L. Clemens +2 more
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Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm. [PDF]
Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Sprinkel KC, Geiger AR, van Hoek ML.
europepmc +2 more sources
Increased knowledge of
Background Recent advances in sequencing technologies offer promising tools for generating large numbers of genomes, larger typing databases and improved mapping of environmental bacterial diversity.
Ahlinder Jon +7 more
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