Results 1 to 10 of about 1,012,172 (301)
Sequestration of host metabolism by an intracellular pathogen [PDF]
eLife, 2016 For intracellular pathogens, residence in a vacuole provides a shelter against cytosolic host defense to the cost of limited access to nutrients. The human pathogen Chlamydia trachomatis grows in a glycogen-rich vacuole.
Lena Gehre +8 more
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The Role of Autophagy in Intracellular Pathogen Nutrient Acquisition
Frontiers in Cellular and Infection Microbiology, 2015 Following entry into host cells intracellular pathogens must simultaneously evade innate host defense mechanisms and acquire energy and anabolic substrates from the nutrient-limited intracellular environment.
Shaun eSteele +2 more
doaj +3 more sources
Crystals, 2018 Legionella pneumophila RpoS (LpRpoS), an alternative sigma factor of RNA polymerase (RNAP), is essential for virulence and stress resistance. To investigate the mechanism of RpoS in the intracellular pathogen L.
Nannan Zhang +7 more
doaj +3 more sources
Autophagy and checkpoints for intracellular pathogen defense. [PDF]
Curr Opin Gastroenterol, 2015 Autophagy plays a crucial role in intracellular defense against various pathogens. Xenophagy is a form of selective autophagy that targets intracellular pathogens for degradation. In addition, several related, yet distinct, intracellular defense responses depend on autophagy-related genes.
Paulus GL, Xavier RJ.
europepmc +4 more sources
Host Epigenetics in Intracellular Pathogen Infections [PDF]
International Journal of Molecular Sciences, 2020 Marcin Włodarczyk +2 more
exaly +2 more sources
Effect of Reactive Oxygen Species on the Endoplasmic Reticulum and Mitochondria during Intracellular Pathogen Infection of Mammalian Cells [PDF]
Antioxidants, 2021 Junghwan Lee, Chang-Hwa Song
exaly +2 more sources
Annulate lamellae and intracellular pathogens [PDF]
Cellular Microbiology, 2021 Annulate lamellae (AL) have been observed many times over the years on electron micrographs of rapidly dividing cells, but little is known about these unusual organelles consisting of stacked sheets of endoplasmic reticulum-derived membranes with nuclear pore complexes (NPCs). Evidence is growing for a role of AL in viral infection.
Eymieux, Sébastien +4 more
openaire +3 more sources
The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development
Emerging Microbes and Infections, 2023 The coronavirus disease 2019 (COVID-19) has caused enormous health risks and global economic disruption. This disease is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Haiyun Yu +4 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Understanding of how intracellular pathogens survive in their host cells is important to improve management of their diseases. This has been fruitful for intracellular bacteria, but it is an understudied area in fungal pathogens.
Emmanuel J. Santiago-Burgos +4 more
doaj +1 more source
The intracellular pathogen concept [PDF]
Molecular Microbiology, 2019 AbstractThe intracellular pathogen concept classifies pathogenic microbes on the basis of their site of replication and dependence on host cells. This concept played a fundamental role in establishing the field of cellular microbiology, founded in part by Dr.
Arturo Casadevall, Ferric C. Fang
openaire +2 more sources