Results 1 to 10 of about 414,264 (159)
The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development
Emerging Microbes and Infections, 2023 The coronavirus disease 2019 (COVID-19) has caused enormous health risks and global economic disruption. This disease is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Haiyun Yu +4 more
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Mycobacterium tuberculosis-macrophage interaction: Molecular updates
Frontiers in Cellular and Infection Microbiology, 2023 Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where it interacts with macrophages.
Haotian Bo +11 more
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Frontiers in Cellular and Infection Microbiology, 2022 Understanding of how intracellular pathogens survive in their host cells is important to improve management of their diseases. This has been fruitful for intracellular bacteria, but it is an understudied area in fungal pathogens.
Emmanuel J. Santiago-Burgos +4 more
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Frontiers in Cellular and Infection Microbiology, 2020 Acinetobacter baumannii is an important causative agent of nosocomial infections worldwide. The pathogen also readily acquires resistance to antibiotics, and pan-resistant strains have been reported. A.
Qing-Ming Qin +8 more
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Exploitation of the Host Ubiquitin System: Means by Legionella pneumophila
Frontiers in Microbiology, 2021 Ubiquitination is a commonly used post-translational modification (PTM) in eukaryotic cells, which regulates a wide variety of cellular processes, such as differentiation, apoptosis, cell cycle, and immunity.
Jingjing Luo +3 more
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A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes
eLife, 2023 Identifying virulence-critical genes from pathogens is often limited by functional redundancy. To rapidly interrogate the contributions of combinations of genes to a biological outcome, we have developed a multiplex, randomized CRISPR interference ...
Nicole A Ellis +7 more
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mBio, 2022 Francisella tularensis, a Tier 1 select agent of bioterrorism, contains a type VI secretion system (T6SS) encoded within the Francisella pathogenicity island (FPI), which is critical for its pathogenesis.
Xiaoyu Liu +5 more
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Q Fever Vaccine Development: Current Strategies and Future Considerations
Pathogens, 2021 Q fever is a zoonotic disease caused by the intracellular pathogen Coxiella burnetii. This disease typically manifests as a self-limiting, febrile illness known as acute Q fever.
Carrie Mae Long
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Brucella: not your ‘typical’ intracellular pathogen [PDF]
Microbiology Australia, 2020 Currently the genus Brucella consists of a group of bacteria that are genetically monospecific yet phenotypically diverse, and a recent genetic and phenotypic divergent group known as ‘atypical' Brucellae.
Nicky Buller, Anthony L Keyburn
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Pathogens, 2023 In 2020, the WHO established the road map for neglected tropical diseases 2021–2030, which aims to control and eradicate 20 diseases, including leishmaniosis and Chagas disease. In addition, since 2015, the WHO has been developing a Global Action Plan on
Sara M. Robledo +7 more
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