Results 1 to 10 of about 56,092 (157)

The paradigm of intracellular parasite survival and drug resistance in leishmanial parasite through genome plasticity and epigenetics: Perception and future perspective [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Leishmania is an intracellular, zoonotic, kinetoplastid eukaryote with more than 1.2 million cases all over the world. The leishmanial chromosomes are divided into polymorphic chromosomal ends, conserved central domains, and antigen-encoding genes found ...
Mohd Kamran   +2 more
exaly   +4 more sources

Influential Parameters for the Analysis of Intracellular Parasite Metabolomics [PDF]

open access: yesmSphere, 2018
Metabolomics is increasingly popular for the study of pathogens. For the malaria parasite Plasmodium falciparum, both targeted and untargeted metabolomics have improved our understanding of pathogenesis, host-parasite interactions, and antimalarial drug ...
Maureen A. Carey   +7 more
doaj   +4 more sources

Stage-Specific and Selective Delivery of Caged Azidosugars into the Intracellular Parasite Toxoplasma gondii by Using an Esterase-Ester Pair Technique [PDF]

open access: yesmSphere, 2019
Toxoplasma gondii is an obligate intracellular parasite that chronically infects up to a third of the human population. The parasites persist in the form of cysts in the central nervous system and serve as a reservoir for the reactivation of toxoplasmic ...
Tadakimi Tomita   +3 more
doaj   +2 more sources

The Biology of the Intestinal Intracellular Parasite Cryptosporidium [PDF]

open access: yesCell Host and Microbe, 2020
Cryptosporidium emerged as a leading global cause of severe diarrheal disease in children. The parasite occupies a unique intracellular niche at the brush border of intestinal epithelial cells, where it undergoes a complex sexual life cycle. How this life cycle unfolds and how host and parasite interact remain largely to be discovered.
Amandine Guerin, Boris Striepen
exaly   +4 more sources

Deleterious Interaction Between Honeybees (Apis mellifera) and its Microsporidian Intracellular Parasite Nosema ceranae Was Mitigated by Administrating Either Endogenous or Allochthonous Gut Microbiota Strains

open access: yesFrontiers in Ecology and Evolution, 2018
Honey bees (Apis mellifera) are facing multiple stressors affecting their lifespan, health and productivity. Among them, Nosema ceranae is an intracellular microsporidian parasite, which plays a major impact on honey bees colonies.
Sarah El Khoury   +2 more
exaly   +3 more sources

Experimental Hybridization in Leishmania: Tools for the Study of Genetic Exchange

open access: yesPathogens, 2022
Despite major advances over the last decade in our understanding of Leishmania reproductive strategies, the sexual cycle in Leishmania has defied direct observation and remains poorly investigated due to experimental constraints.
Tiago R. Ferreira, David L. Sacks
doaj   +1 more source

Salmonella as an intracellular parasite [PDF]

open access: yesMolecular Microbiology, 1989
SummarySalmonella species are facultative intracellular parasites, capable of penetrating (invading), surviving, and often multiplying within diverse eukaryotic cell types, including epithelial and phagocytic cells. These processes are essential for virulence, and involve both bacterial and host cell products.
B B, Finlay, S, Falkow
openaire   +2 more sources

The Leishmania donovani LDBPK_220120.1 Gene Encodes for an Atypical Dual Specificity Lipid-Like Phosphatase Expressed in Promastigotes and Amastigotes; Substrate Specificity, Intracellular Localizations, and Putative Role(s)

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The intracellular protozoan parasites of the Leishmania genus are responsible for Leishmaniases, vector borne diseases with a wide range of clinical manifestations.
Amalia Papadaki   +14 more
doaj   +1 more source

Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection

open access: yeseLife, 2021
Toxoplasma gondii is an important human pathogen infecting an estimated one in three people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restriction is
Nicholas Rinkenberger   +5 more
doaj   +1 more source

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