Results 11 to 20 of about 65,062 (302)

The enemy within: lipid asymmetry in intracellular parasite-host interactions. [PDF]

Emerg Top Life Sci, 2023
Eukaryotic pathogens with an intracellular parasitic lifestyle are shielded from extracellular threats during replication and growth. In addition to many nutrients, parasites scavenge host cell lipids to establish complex membrane structures inside their
Fraser M, Matuschewski K, Maier AG.
europepmc   +2 more sources

Phagocytosis Is the Sole Arm of Drosophila melanogaster Known Host Defenses That Provides Some Protection Against Microsporidia Infection

Frontiers in Immunology, 2022
Microsporidia are obligate intracellular parasites able to infest specifically a large range of species, including insects. The knowledge about the biology of microsporidial infections remains confined to mostly descriptive studies, including molecular ...
Gaëtan Caravello, Adrien Franchet, Sebastian Niehus, Dominique Ferrandon   +3 more
doaj   +1 more source

Mechanisms Associated with Trypanosoma cruzi Host Target Cell Adhesion, Recognition and Internalization

Life, 2021
Chagas disease is caused by the kinetoplastid parasite Trypanosoma cruzi, which is mainly transmitted by hematophagous insect bites. The parasite’s lifecycle has an obligate intracellular phase (amastigotes), while metacyclic and bloodstream ...
Oscar Hernán Rodríguez-Bejarano, Catalina Avendaño, Manuel Alfonso Patarroyo   +2 more
doaj   +1 more source

An Extracellular Redox Signal Triggers Calcium Release and Impacts the Asexual Development of Toxoplasma gondii

Frontiers in Cellular and Infection Microbiology, 2021
The ability of an organism to sense and respond to environmental redox fluctuations relies on a signaling network that is incompletely understood in apicomplexan parasites such as Toxoplasma gondii.
Eduardo Alves, Henry J. Benns, Henry J. Benns, Lilian Magnus, Caia Dominicus, Tamás Dobai, Joshua Blight, Ceire J. Wincott, Matthew A. Child   +8 more
doaj   +1 more source

Diverse Requirements for Src-Family Tyrosine Kinases Distinguish Chlamydial Species

mBio, 2011
Chlamydiae are well known for their species specificity and tissue tropism, and yet the individual species and strains show remarkable genomic synteny and share an intracellular developmental cycle unique in the microbial world.
Jeffrey Mital, Ted Hackstadt
doaj   +1 more source

Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites [PDF]

, 2014
EH and TAW acknowledge support from the Marie Curie Fellowship Programme (HTTP://cordis.europa.eu/fp7/home_en.html). ERSK, JML and TME acknowledge support from the Wellcome Trust (www.wellcome.ac.uk/).
Eva Heinz (105025), Hirt, R.P., Edmund R. S. Kunji (669696), Williams, Tom A, Goldberg, A.V., Robert P Hirt, Hacker Christian, T Martin Embley, Robert P. Hirt (124609), Kunji, E.R.S., Nakjang, Sirintra, Hirt, Robert, Kunji, Edmund R S, John M. Lucocq (124603), Embley, T. Martin, Christian Hacker (124601), Edmund R S Kunji, Alina V. Goldberg (124596), Heinz, Eva, John Mifsud (669694), Lucocq, John M., Alison Gregory, Embley T. Martin, Dean, P., Hirt, Robert P., Goldberg, Alina V, Heinz, E., Nakjang Sirintra, T. Martin Embley (124611), Williams Tom A., Sirintra Nakjang (124590), Kunji, Edmund R. S., Kunji, Edmund, John M Lucocq, Gregory, Alison, Goldberg, Alina, Goldberg Alina V., Tom A Williams, Tom A. Williams (124587), Gregory, A., Lucocq John M., Embley, T Martin, Paul Dean (35800), Heinz Eva, Dean, Paul; id_orcid, John Mifsud, Williams, Tom A., Lucocq, John M, Hirt Robert P., Alina V Goldberg, Dean, Paul, Hirt, Robert P, Paul Dean, Nakjang, S., Embley, T, Sirintra Nakjang, Gregory Alison, Dean Paul, Goldberg, Alina V., Mifsud, John, Lucocq, John, Williams, T.A., Mifsud John, Christian Hacker, Alison Gregory (669695), Embley, T.M., Williams, Tom, Eva Heinz, Hacker, Christian, Hacker, C., Kunji, Edmund R.S., Mifsud, J., Kunji Edmund R. S.   +72 more
core   +1 more source

The Mechanism of Facultative Intracellular Parasitism of Brucella [PDF]

International Journal of Molecular Sciences, 2021
Brucellosis is a highly prevalent zoonotic disease characterized by abortion and reproductive dysfunction in pregnant animals. Although the mortality rate of Brucellosis is low, it is harmful to human health, and also seriously affects the development of animal husbandry, tourism and international trade.
Jiao, Hanwei, Zhou, Zhixiong, Li, Bowen, Xiao, Yu, Li, Mengjuan, Zeng, Hui, Guo, Xiaoyi, Gu, Guojing   +7 more
openaire   +2 more sources

Modulation of NF-kappaB activation in Theileria annulata-infected cloned cell lines is associated with detection of parasite-dependent IKK signalosomes and disruption of the actin cytoskeleton [PDF]

, 2010
Apicomplexan parasites within the genus <i>Theileria</i> have the ability to induce continuous proliferation and prevent apoptosis of the infected bovine leukocyte.
Weir, W., Hermann, P., McKellar, S., Dobbelaere, D., Dobbelaere, Dirk,, Schmuckli-Maurer, J., Pillai, S., Shiels, B., Kinnaird, J.   +8 more
core   +1 more source

Targeted Knockout of the Rickettsia rickettsii OmpA Surface Antigen Does Not Diminish Virulence in a Mammalian Model System

mBio, 2015
Strains of Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever (RMSF), differ dramatically in virulence despite >99% genetic homology.
Nicholas F. Noriea, Tina R. Clark, Ted Hackstadt   +2 more
doaj   +1 more source

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. [PDF]

, 2013
The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV). Eventually, in a tightly regulated process called egress, proteins of the PV and intracellular merozoite surface are modified by an essential parasite serine ...
Baker, David A, Strath Malcolm, Maria Penzo, David A Baker, Hackett Fiona, Penzo, Maria, Blackman, Michael J, Michael J Blackman, David A. Baker (122252), Christine R Collins, Fiona Hackett (27620), Christine R. Collins, Strath, Malcolm, Withers-Martinez, Chrislaine, David A. Baker, Michael J. Blackman, Malcolm Strath (411645), Withers-Martinez Chrislaine, Penzo Maria, Chrislaine Withers-Martinez, Malcolm Strath, Collins Christine R., Hackett, Fiona, Fiona Hackett, Chrislaine Withers-Martinez (27619), Baker David A., Collins, Christine R, Christine R. Collins (191982), Michael J. Blackman (192013), Blackman Michael J., Maria Penzo (411646)   +30 more
core   +1 more source