Results 21 to 30 of about 65,062 (302)

Chlamydia trachomatis Inclusion Membrane Protein CT228 Recruits Elements of the Myosin Phosphatase Pathway to Regulate Release Mechanisms

Cell Reports, 2013
Chlamydia trachomatis replicates within a membrane-bound compartment termed an inclusion. The inclusion membrane is modified by the insertion of multiple proteins known as Incs. In a yeast two-hybrid screen, an interaction was found between the inclusion
Erika I. Lutter, Alexandra C. Barger, Vinod Nair, Ted Hackstadt   +3 more
doaj   +1 more source

Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]

, 2013
Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Howell, Matthew, Hacker, Christian, Lucocq, John Milton, Lucocq, John, Bhella, David   +4 more
core   +1 more source

The Complexity of Interferon Signaling in Host Defense against Protozoan Parasite Infection

Pathogens, 2023
Protozoan parasites, such as Plasmodium, Leishmania, Toxoplasma, Cryptosporidium, and Trypanosoma, are causative agents of health-threatening diseases in both humans and animals, leading to significant health risks and socioeconomic losses globally.
Silu Deng, Marion L. Graham, Xian-Ming Chen   +2 more
doaj   +1 more source

Host triacylglycerols shape the lipidome of intracellular trypanosomes and modulate their growth. [PDF]

PLoS Pathogens, 2017
Intracellular infection and multi-organ colonization by the protozoan parasite, Trypanosoma cruzi, underlie the complex etiology of human Chagas disease. While T.
Felipe Gazos-Lopes, Jessica L Martin, Peter C Dumoulin, Barbara A Burleigh   +3 more
doaj   +1 more source

Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity [PDF]

, 2008
<i>Plasmodium falciparum</i> sporozoites that develop and mature inside an <i>Anopheles</i> mosquito initiate a malaria infection in humans.
Lasonder Edwin, Edwin Lasonder, Khan, Shahid M., Geert-Jan van Gemert, Mair, G. R., Gunnar R Mair, Stunnenberg Hendrik G., Waters, A.P., Mann, Matthias, van Gemert, G. J., Vermunt Adriaan M. W., Mair Gunnar R., Huynen, Martijn A., Shahid M Khan, Kroeze Hans, Stunnenberg, Hendrik G, Mair, Gunnar R., van Gemert, Geert-Jan, Janse, C., van Gemert Geert-Jan, Sauerwein, R., Stunnenberg, H. G., Janse, C.J., Mann, M., Kroeze, H., Vermunt, Adriaan M. W., Bruno G Douradinha, Luty, A., Vermunt, A.M.W., Khan, S. M., Khan, S., Vermunt, Adriaan M W, Khan, Shahid M, Chris J Janse, Sauerwein Robert W., van Gemert, G.J., Douradinha, Bruno G., Hans Kroeze, Adriaan M W Vermunt, Sauerwein, R. W., Robert W Sauerwein, Sauerwein, Robert W., Adrian J F Luty, Andrew P Waters, Kroeze, Hans, Sauerwein, Robert W, Douradinha, B.G., Luty, Adrian J F, Mann Matthias, Waters Andrew P., Lasonder, Edwin, van Noort, V., Luty, A.J.F., Sauerwein, R.W., Luty, A. J., Huynen Martijn A., Gemert, G.J.A. van, Douradinha, B. G., Mair, G.R., Douradinha, B., Khan, S.M., van Noort Vera, Huynen, Martijn A, Noort, V. van, Vera van Noort, Mair, Gunnar R, Janse, Chris J., Khan Shahid M., Stunnenberg, H., van Noort, Vera, Hendrik G Stunnenberg, Douradinha Bruno G., Lasonder, E., Janse, Chris J, Mair, G., Huynen, M., Matthias Mann, Vermunt, A. M., Waters, A. P., Janse, C. J., Waters, Andrew P, Luty Adrian J. F., van Gemert, G., Waters, A., Waters, Andrew P., Stunnenberg, H.G., Douradinha, Bruno G, Janse Chris J., Stunnenberg, Hendrik G., Luty, Adrian J. F., Huynen, M.A., Martijn A Huynen, Vermunt, A., Huynen, M. A.   +93 more
core   +1 more source

Transcriptional Analyses Identify Genes That Modulate Bovine Macrophage Response to Toxoplasma Infection and Immune Stimulation

Frontiers in Cellular and Infection Microbiology, 2020
The obligate intracellular parasite, Toxoplasma gondii, is highly prevalent among livestock species. Although cattle are generally resistant to Toxoplasma strains circulating in Europe and North America, the underlying mechanisms are largely unknown ...
Anton Gossner, Musa A. Hassan, Musa A. Hassan   +2 more
doaj   +1 more source

Studies on interactions of exported "plasmodium falciparum" membrane proteins [PDF]

, 2014
Responsible for about 700’000 annual deaths worldwide, malaria today is still one of the major health problems in developing countries. The most deadly form of human malaria called malaria tropica is caused by the apicomplexan parasite Plasmodium ...
Dietz, Olivier
core   +1 more source

Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.

PLoS Pathogens, 2020
Ubiquitylation is a common post translational modification of eukaryotic proteins and in the human malaria parasite, Plasmodium falciparum (Pf) overall ubiquitylation increases in the transition from intracellular schizont to extracellular merozoite ...
Judith L Green, Yang Wu, Vesela Encheva, Edwin Lasonder, Adchara Prommaban, Simone Kunzelmann, Evangelos Christodoulou, Munira Grainger, Ngoc Truongvan, Sebastian Bothe, Vikram Sharma, Wei Song, Irene Pinzuti, Chairat Uthaipibull, Somdet Srichairatanakool, Veronique Birault, Gordon Langsley, Hermann Schindelin, Benjamin Stieglitz, Ambrosius P Snijders, Anthony A Holder   +20 more
doaj   +1 more source

The Intracellular Amastigote of Trypanosoma cruzi Maintains an Actively Beating Flagellum

mBio, 2023
Throughout its complex life cycle, the uniflagellate parasitic protist, Trypanosoma cruzi, adapts to different host environments by transitioning between elongated motile extracellular stages and a nonmotile intracellular amastigote stage that replicates
Madalyn M. Won, Timothy Krüger, Markus Engstler, Barbara A. Burleigh   +3 more
doaj   +1 more source

The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission [PDF]

, 2009
1Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp.
Vega-Rodríguez Joel, Franke-Fayard Blandine, Coppens Isabelle, Waters Andrew P., Dinglasan, R.R., Andrew P. Waters, Joel Vega-Rodríguez, Rhoel R. Dinglasan, Jacobs-Lorena Marcelo, José F Rodríguez-Orengo, Jacobs-Lorena, M., Rodríguez-Orengo José F., Blandine Franke-Fayard, Chris J. Janse, Vega-Rodriguez, J., Isabelle Coppens, José F. Rodríguez-Orengo, Serrano Adelfa E., Adelfa E. Serrano, Janse, C.J., Serrano, A.E., Rhoel R Dinglasan, Prakash Srinivasan, Waters, A., Adelfa E Serrano, Marcelo Jacobs-Lorena, Pastrana-Mena Rebecca, Janse Chris J., Chris J Janse, Dinglasan Rhoel R., Rodriguez-Orengo, J.F., Srinivasan, P., Pastrana-Mena, R., Rebecca Pastrana-Mena, Franke-Fayard, B., Andrew P Waters   +35 more
core   +1 more source