Results 11 to 20 of about 1,064,501 (255)

Purification and proteomics of pathogen-modified vacuoles and membranes [PDF]

Frontiers in Cellular and Infection Microbiology, 2015
Certain pathogenic bacteria adopt an intracellular lifestyle and proliferate in eukaryotic host cells. The intracellular niche protects the bacteria from cellular and humoral components of the mammalian immune system, and at the same time, allows the ...
Jo-Ana eHerweg, Nicole eHansmeier, Andreas eOtto, Anna eGeffken, Prema eSubbarayal, Bhupesh ePrusty, Dörte eBecher, Michael eHensel, Ulrich Emil Schaible, Thomas eRudel, Hubert eHilbi   +10 more
doaj   +2 more sources

Effect of Reactive Oxygen Species on the Endoplasmic Reticulum and Mitochondria during Intracellular Pathogen Infection of Mammalian Cells. [PDF]

Antioxidants (Basel), 2021
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune signals, induce autophagy and activate inflammation.
Lee J, Song CH.
europepmc   +2 more sources

Human guanylate-binding proteins in intracellular pathogen detection, destruction, and host cell death induction [PDF]

, 2023
Cell-intrinsic defense is an essential part of the immune response against intracellular pathogens regulated by cytokine-induced proteins and pathways.
Frickel, Eva-Maria, Barbara Clough, Rivera-Cuevas, Yolanda, Yolanda Rivera-Cuevas, Clough, Barbara, Clough, Barbara; id_orcid, Eva-Maria Frickel, Frickel, Eva Maria   +7 more
core   +1 more source

Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche.

Cell Rep, 2019
International audienceSalmonella is a human and animal pathogen that causes gastro-enteric diseases. The key to Salmonella infection is its entry into intestinal epithelial cells, where the bacterium resides within a Salmonella-containing vacuole (SCV ...
Stévenin V, Chang YY, Le Toquin Y, Duchateau M, Gianetto QG, Luk CH, Salles A, Sohst V, Matondo M, Reiling N, Enninga J.   +10 more
europepmc   +2 more sources

Invasion and persistent intracellular colonization of erythrocytes : A unique parasitic strategy of the emerging pathogen Bartonella [PDF]

, 2001
The expanding genus Bartonella includes zoonotic and human-specific pathogens that can cause a wide range of clinical manifestations. A productive infection allowing bacterial transmission by blood-sucking arthropods is marked by an intraerythrocytic ...
Schulein, R., Gille, C., Yves Hansmann, Hansmann, Y., Dehio, C., Seubert, A., Piemont, Y., Yves Piémont, Christa Lanz, Ralf Schülein, Anja Seubert, Lanz, C., Christoph Dehio, Christian Gille, Hansmann Y, Piémont Y, Gille C, Seubert A, Schülein R, Dehio C, Lanz C   +20 more
core   +1 more source

Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen burkholderia pseudomallei K96243 [PDF]

, 2010
Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions, including South East Asia and Northern Australia, where it causes melioidosis, a serious disease ...
Wilkinson Paul A., Dowling, Andrea J., Matthew T G Holden, Richard W. Titball, Nicholas R. Waterfield, Paul A Wilkinson, Titball, Richard W., Bentley Stephen D., Holden Matthew T. G., Richard W Titball, Julia Reger, Quail, Michael A., Waterfield Nicholas R., Stephen D. Bentley, Andrea J Dowling, Stephen D Bentley, Wilkinson, Paul A., Bentley, Stephen D., Holden, Matthew T. G., ffrench-Constant, Richard H., ffrench-Constant Richard H., Richard H. ffrench-Constant, Paul A. Wilkinson, Matthew T. G. Holden, Michael A. Quail, Michael A Quail, Waterfield, Nicholas R., Dowling Andrea J., Titball Richard W., Nicholas R Waterfield, Reger, Julia, Quail Michael A., Andrea J. Dowling, Andrea J. Dowling, Richard H Ffrench-Constant, Reger Julia, Holden, Matthew T. G.; id_orcid   +36 more
core   +1 more source

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages. [PDF]

, 2008
BACKGROUND: Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium ...
Waddell, Simon, Castagnoli, PR, Mattia Pelizzola (20247), Castagnoli, Paola Ricciardi, Pelizzola Mattia, Foti, M, Maria Foti, Butcher, Philip, Neyrolles, Olivier, Neyrolles, O, Antoine Tanne, Simon J Waddell, Olivier Neyrolles, Pelizzola, M, Tailleux, L, Simon J. Waddell, Antoine Tanne (272975), Philip D Butcher (16047203), Maria Foti (20249), Neil G. Stoker, Stoker Neil G., Waddell, SJ, Tailleux Ludovic, Tailleux, Ludovic, Gicquel, Brigitte, Simon Waddell (4462816), Castagnoli Paola Ricciardi, Brigitte Gicquel, Philip D Butcher, Tanne Antoine, Alessandra Mortellaro (272973), Mortellaro, A, Gicquel Brigitte, Stoker, Neil, Philip D. Butcher, Butcher, PD, Tanne, Antoine, Olivier Neyrolles (72204), Tanne, A, Mortellaro, Alessandra, Paola Ricciardi Castagnoli (16048310), Ludovic Tailleux, Michael Withers (272974), Neyrolles Olivier, Withers Michael, Foti, Maria, Waddell Simon J., Stoker, NG, Michael Withers, Pelizzola, Mattia, Mortellaro Alessandra, Brigitte Gicquel (31454), Ludovic Tailleux (72195), Neil G Stoker (16048313), Alessandra Mortellaro, Neil G Stoker, Foti Maria, Gicquel, B, Butcher Philip D., Withers, M, Mattia Pelizzola, Paola Ricciardi Castagnoli, Withers, Michael, Waddel S.J., Withers M., Neyrolles O., Tanne A., Tailleux L., Foti M., Stoker N.G., Butcher P.D., Pelizzola M., Mortellaro A., Gicquel B., Castagnoli P.R.   +74 more
core   +1 more source

Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System

mBio, 2022
Francisella tularensis, a Tier 1 select agent of bioterrorism, contains a type VI secretion system (T6SS) encoded within the Francisella pathogenicity island (FPI), which is critical for its pathogenesis.
Xiaoyu Liu, Daniel L. Clemens, Bai-Yu Lee, Xue Yang, Z. Hong Zhou, Marcus A. Horwitz   +5 more
doaj   +1 more source

Q Fever Vaccine Development: Current Strategies and Future Considerations

Pathogens, 2021
Q fever is a zoonotic disease caused by the intracellular pathogen Coxiella burnetii. This disease typically manifests as a self-limiting, febrile illness known as acute Q fever.
Carrie Mae Long
doaj   +1 more source

Intra-ChIP: studying gene regulation in an intracellular pathogen. [PDF]

Curr Genet, 2016
Intracellular bacteria that reside within a host cell use a variety of strategies to exploit this unique niche. While these organisms are technically challenging to study in the context of an infected host cell, recent advances have led to an improved ...
Hanson BR, Tan M.
europepmc   +2 more sources