Results 11 to 20 of about 1,012,172 (301)

Intra-ChIP: studying gene regulation in an intracellular pathogen [PDF]

Current Genetics, 2016
Intracellular bacteria that reside within a host cell use a variety of strategies to exploit this unique niche. While these organisms are technically challenging to study in the context of an infected host cell, recent advances have led to an improved ...
Ming Tan
exaly   +4 more sources

Exploitation of the Host Ubiquitin System: Means by Legionella pneumophila

Frontiers in Microbiology, 2021
Ubiquitination is a commonly used post-translational modification (PTM) in eukaryotic cells, which regulates a wide variety of cellular processes, such as differentiation, apoptosis, cell cycle, and immunity.
Jingjing Luo, Lidong Wang, Lei Song, Zhao-Qing Luo   +3 more
doaj   +1 more source

Epidemiology of intracellular pathogens [PDF]

Clinical Microbiology and Infection, 1996
Epidemiologic studies of Chlamydia pneumoniae have been conducted throughout the world. A rate of antibody prevalence of approximately 50% has been found in adults, with small regional differences. We studied the antibody prevalence of C. pneumoniae in healthy persons and patients with acute respiratory infections in Japan.
Niki, Yoshito, Kishimoto, Toshio
openaire   +2 more sources

Persistent intracellular pathogens [PDF]

FEMS Microbiology Reviews, 2012
Intracellular pathogens live and replicate either within endosomal compartments or in the cytosol of diverse host cells such as macrophages, dendritic cells, neutrophils, fibroblasts, epithelial or endothelial cells or erythrocytes. Examples not only include all viruses, which represent obligate intracellular pathogens in the strictest sense, but also ...
Dehio, C., Berry, C., Bartenschlager, R.
openaire   +3 more sources

Mycobacterium tuberculosis-macrophage interaction: Molecular updates

Frontiers in Cellular and Infection Microbiology, 2023
Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where it interacts with macrophages.
Haotian Bo, Ulrich Aymard Ekomi Moure, Ulrich Aymard Ekomi Moure, Yuanmiao Yang, Jun Pan, Li Li, Miao Wang, Xiaoxue Ke, Xiaoxue Ke, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +11 more
doaj   +1 more source

Transcriptional adaptation of shigella flexneri during infection of macrophages and epithelial cells : insights into the strategies of a cytosolic bacterial pathogen [PDF]

, 2004
Shigella flexneri, the etiologic agent of bacillary dysentery, invades epithelial cells as well as macrophages and dendritic cells and escapes into the cytosol soon after invasion.
Hong Liu, Lucchini, Sacha, Qi, J., Sacha Lucchini, S. Lucchini, Jin, Qi, Hinton, Jay C. D., Qi Jin, H. Liu, Liu, Hong, J. C. D. Hinton, Lucchini, S., Hinton, J.C.D., Jay C. D. Hinton, Yu, J., Jun Yu, J. Yu, Liu, H., Q. Jin, Yu, Jun   +19 more
core   +4 more sources

A Tractable Drosophila Cell System Enables Rapid Identification of Acinetobacter baumannii Host Factors

Frontiers in Cellular and Infection Microbiology, 2020
Acinetobacter baumannii is an important causative agent of nosocomial infections worldwide. The pathogen also readily acquires resistance to antibiotics, and pan-resistant strains have been reported. A.
Qing-Ming Qin, Qing-Ming Qin, Jianwu Pei, Gabriel Gomez, Allison Rice-Ficht, Thomas A. Ficht, Paul de Figueiredo, Paul de Figueiredo, Paul de Figueiredo   +8 more
doaj   +1 more source

A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes

eLife, 2023
Identifying virulence-critical genes from pathogens is often limited by functional redundancy. To rapidly interrogate the contributions of combinations of genes to a biological outcome, we have developed a multiplex, randomized CRISPR interference ...
Nicole A Ellis, Kevin S Myers, Jessica Tung, Anne Davidson Ward, Kathryn Johnston, Katherine E Bonnington, Timothy J Donohue, Matthias P Machner   +7 more
doaj   +1 more source

Brucella: not your ‘typical’ intracellular pathogen [PDF]

Microbiology Australia, 2020
Currently the genus Brucella consists of a group of bacteria that are genetically monospecific yet phenotypically diverse, and a recent genetic and phenotypic divergent group known as ‘atypical' Brucellae.
Nicky Buller, Anthony L Keyburn
doaj  

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development [PDF]

, 2011
Rhodococcus equi causes fatal pyogranulomatous pneumonia in foals and immunocompromised animals and humans. Despite its importance, there is currently no effective vaccine against the disease. The actinobacteria R.
Hessels G. I., L. Dijkhuizen, Dijkhuizen, L.,, R van der Geize, Grommen A. W. F., G. I. Hessels, R. van der Geize, Grommen, A.W.F.,, L Dijkhuizen, Geize, R. van der,, Dijkhuizen, L., Hessels, G. I., A W F Grommen, Grommen, A. W. F., Jacobs, A.A.C.,, A A C Jacobs, Dijkhuizen, L.; id_orcid, A. A. C. Jacobs, Jacobs, A. A. C., Dijkhuizen L., van der Geize, R., G I Hessels, Jacobs A. A. C., Hessels, G.I.,, A. W. F. Grommen, van der Geize R.   +25 more
core   +3 more sources