Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections [PDF]
In 2019, it was estimated that 2.5 million people die from lower tract respiratory infections annually. One of the main causes of these infections is Staphylococcus aureus, a bacterium that can invade and survive within mammalian cells. S.
Thomas Kuhn +23 more
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Cross-regulation in a three-component cell envelope stress signaling system of Brucella
A multi-layered structure known as the cell envelope separates the controlled interior of bacterial cells from a fluctuating physical and chemical environment.
Xingru Chen +3 more
doaj +1 more source
A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Hermon-Taylor, J +11 more
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Intracellular phase for an extracellular bacterial pathogen: MgtC shows the way
Pseudomonas aeruginosa is an extracellular pathogen known to impair host phagocytic functions. However, our recent results identify MgtC as a novel actor in P.
Audrey Bernut +9 more
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Mycoredoxins Are Required for Redox Homeostasis and Intracellular Survival in the Actinobacterial Pathogen Rhodococcus equi [PDF]
[EN] Rhodococcus equi is a facultative intracellular pathogen that can survive within macrophages of a wide variety of hosts, including immunosuppressed humans.
Mourenza Flórez, Álvaro +5 more
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Brucella abortus egresses from host cells in infective clusters through an actin-dependent mechanism
Brucella abortus is an intracellular pathogen whose cell cycle encompasses attachment, internalization, trafficking, replication, and egress from host cells.
José Fabio Campos-Godínez +14 more
doaj +1 more source
Neutrophils are important assets in defense against invading bacteria like staphylococci. However, (dysfunctioning) neutrophils can also serve as reservoir for pathogens that are able to survive inside the cellular environment. Staphylococcus aureus is a
Suzanne Bongers +4 more
doaj +1 more source
Study on the Occurrence of Genetic Exchange Among Parasites of the Leishmania mexicana Complex
In Leishmania, genetic exchange has been experimentally demonstrated to occur in the sand fly vector and in promastigote axenic cultures through a meiotic-like process.
Roman Telittchenko, Albert Descoteaux
doaj +1 more source
Coxiella burnetii Sterol-Modifying Protein Stmp1 Regulates Cholesterol in the Intracellular Niche
Coxiella burnetii replicates in a phagolysosome-like vacuole called the Coxiella-containing vacuole (CCV). While host cholesterol readily traffics to the CCV, cholesterol accumulation leads to CCV acidification and bacterial death.
Tatiana M. Clemente +6 more
doaj +1 more source
Genome Sequence of the Obligate Intracellular Animal Pathogen Chlamydia pecorum E58 [PDF]
Chlamydia pecorum is an obligate intracellular bacterial pathogen that causes diverse disease in a wide variety of economically important mammals. We report the finished complete genome sequence of C. pecorum E58, the type strain for the species. © 2011,
Myers, GSA +15 more
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