Results 31 to 40 of about 1,012,172 (301)
Nature Communications, 2023 The bacterium Brucella abortus is an intracellular pathogen that modulates autophagy in host cells. Here, the authors identify two B. abortus effectors that interact with host protease SENP3, thus promoting cytoplasmic accumulation of nucleolar proteins ...
Arthur Louche +15 more
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No better time to FRET: shedding light on host pathogen interactions [PDF]
, 2010 Understanding the spatio-temporal subversion of host cell signaling by bacterial virulence factors is key to combating infectious diseases. Following a recent study by Buntru and co-workers published in BMC Biology, we review how fluorescence (Forster ...
Leong, J.M. +5 more
core +1 more source
Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections [PDF]
, 2020 In 2019, it was estimated that 2.5 million people die from lower tract respiratory infections annually. One of the main causes of these infections is Staphylococcus aureus, a bacterium that can invade and survive within mammalian cells. S.
Thomas Kuhn +23 more
core +1 more source
Antibiotics, 2019 Neutrophils are important assets in defense against invading bacteria like staphylococci. However, (dysfunctioning) neutrophils can also serve as reservoir for pathogens that are able to survive inside the cellular environment. Staphylococcus aureus is a
Suzanne Bongers +4 more
doaj +1 more source
Cell Rep, 2019 International audienceSalmonella is a human and animal pathogen that causes gastro-enteric diseases. The key to Salmonella infection is its entry into intestinal epithelial cells, where the bacterium resides within a Salmonella-containing vacuole (SCV ...
Stévenin V +10 more
europepmc +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 The facultative intracellular pathogen Salmonella enterica Typhimurium (STM) resides in a specific membrane-bound compartment termed the Salmonella-containing vacuole (SCV).
Jennifer Röder +3 more
doaj +1 more source
Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]
, 2014 Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hayward, Richard +5 more
core +1 more source
Purification and proteomics of pathogen-modified vacuoles and membranes
Frontiers in Cellular and Infection Microbiology, 2015 Certain pathogenic bacteria adopt an intracellular lifestyle and proliferate in eukaryotic host cells. The intracellular niche protects the bacteria from cellular and humoral components of the mammalian immune system, and at the same time, allows the ...
Jo-Ana eHerweg +10 more
doaj +1 more source
Cross-regulation in a three-component cell envelope stress signaling system of Brucella
mBio, 2023 A multi-layered structure known as the cell envelope separates the controlled interior of bacterial cells from a fluctuating physical and chemical environment.
Xingru Chen +3 more
doaj +1 more source
An Intracellular Pathogen Response Pathway Promotes Proteostasis in C. elegans. [PDF]
Curr Biol, 2017 Maintenance of protein homeostasis, or proteostasis, is crucial for organismal health. Disruption of proteostasis can lead to the accumulation of protein aggregates, which are associated with aging and many human diseases such as Alzheimer's disease [1-3]
Reddy KC +7 more
europepmc +2 more sources