Results 41 to 50 of about 414,264 (159)

Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]

open access: yes, 2018
Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I   +7 more
core   +2 more sources

An intracellular bacterial pathogen triggers RIG-I/MDA5-dependent necroptosis

open access: yesCurrent Research in Microbial Sciences
RIG-I and MDA5 are members of RIG-I-like receptors (RLRs) that detect viral RNA within the cytoplasm and subsequently initiate antiviral immune responses.
Hang Xu, Huili Li, Boguang Sun, Li Sun
doaj   +1 more source

Amphibian chytridiomycosis : a review with focus on fungus-host interactions [PDF]

open access: yes, 2015
Amphibian declines and extinctions are emblematic for the current sixth mass extinction event. Infectious drivers of these declines include the recently emerged fungal pathogens Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans ...
Haesebrouck, Freddy   +3 more
core   +4 more sources

Host Lipid Transport Protein ORP1 Is Necessary for Coxiella burnetii Growth and Vacuole Expansion in Macrophages

open access: yesmSphere, 2023
Coxiella burnetii is an intracellular bacterium that causes the human disease Q fever. C. burnetii forms a large, acidic Coxiella-containing vacuole (CCV) and uses a type 4B secretion system to secrete effector proteins into the host cell cytoplasm ...
Baleigh Schuler   +2 more
doaj   +1 more source

Presence of Waddlia chondrophila in hot water systems from non-domestic buildings in France [PDF]

open access: yes, 2018
Postprint (author's final ...
Agustí Adalid, Gemma   +4 more
core   +2 more sources

The plant-pathogen haustorial interface at a glance [PDF]

open access: yes, 2020
Many filamentous pathogens invade plant cells through specialized hyphae called haustoria. These infection structures are enveloped by a newly synthesized plant-derived membrane called the extrahaustorial membrane (EHM).
Bozkurt, Tolga O., Kamoun, Sophien
core   +1 more source

Chlamydia trachomatis modulates the expression of JAK-STAT signaling components to attenuate the type II interferon response of epithelial cells

open access: yesmBio
Chlamydia trachomatis has adapted to subvert signaling in epithelial cells to ensure successful intracellular development. Interferon-γ (IFNγ) produced by recruited lymphocytes signals through the JAK/STAT pathway to restrict chlamydial growth in the ...
Francis L. Fontanilla   +3 more
doaj   +1 more source

TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress [PDF]

open access: yes, 2016
Background: Staphylococcus aureus is the principle causative pathogen of osteomyelitis and implant-associated bone infections. It is able to invade and to proliferate inside osteoblasts thus avoiding antibiotic therapy and the host immune system ...
Alt, Volker   +7 more
core   +2 more sources

Intracellular Staphylococcus aureus Modulates Host Central Carbon Metabolism To Activate Autophagy

open access: yesmSphere, 2018
Staphylococcus aureus is a facultative intracellular pathogen that invades and replicates within many types of phagocytic and nonphagocytic cells. During intracellular infection, S. aureus is capable of subverting xenophagy and escaping to the cytosol of
Natalia Bravo-Santano   +6 more
doaj   +1 more source

Pathogen-reactive T helper cell analysis in the pig [PDF]

open access: yes, 2017
There is growing interest in studying host-pathogen interactions in human-relevant large animal models such as the pig. Despite the progress in developing immunological reagents for porcine T cell research, there is an urgent need to directly assess ...
Agnone   +63 more
core   +4 more sources

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