Results 61 to 70 of about 281,844 (353)
Human guanylate-binding proteins in intracellular pathogen detection, destruction, and host cell death induction [PDF]
, 2023 Cell-intrinsic defense is an essential part of the immune response against intracellular pathogens regulated by cytokine-induced proteins and pathways.
Frickel, Eva-Maria +7 more
core +1 more source
Molecular motors hijacking by intracellular pathogens [PDF]
Cellular Microbiology, 2006 Cargoes are transported intracellularly along cytoskeletal tracks composed of actin or tubulin. Their movement involves the action of molecular motor proteins that generate directed movement along microtubules or actin filaments. The three classes of molecular motors--kinesins, dyneins and myosins--are involved in a multiplicity of biological movements
Henry, T., Gorvel, J.P., Meresse, S.
openaire +3 more sources
Purification and proteomics of pathogen-modified vacuoles and membranes
Frontiers in Cellular and Infection Microbiology, 2015 Certain pathogenic bacteria adopt an intracellular lifestyle and proliferate in eukaryotic host cells. The intracellular niche protects the bacteria from cellular and humoral components of the mammalian immune system, and at the same time, allows the ...
Jo-Ana eHerweg +10 more
doaj +1 more source
Autophagy and checkpoints for intracellular pathogen defense. [PDF]
Curr Opin Gastroenterol, 2015 Autophagy plays a crucial role in intracellular defense against various pathogens. Xenophagy is a form of selective autophagy that targets intracellular pathogens for degradation. In addition, several related, yet distinct, intracellular defense responses depend on autophagy-related genes.
Paulus GL, Xavier RJ.
europepmc +4 more sources
Intracellular innate resistance to bacterial pathogens [PDF]
Cellular Microbiology, 2006 Mammalian innate immunity stimulates antigen-specific immune responses and acts to control infection prior to the onset of adaptive immunity. Some bacterial pathogens replicate within the host cell and are therefore sheltered from some protective aspects of innate immunity such as complement.
Radtke, Andrea Lynn +1 more
openaire +3 more sources
Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence [PDF]
, 2013 Pathogen access to host nutrients in infected tissues is fundamental for pathogen growth and virulence, disease progression, and infection control. However, our understanding of this crucial process is still rather limited because of experimental and ...
Burton, Neil A +32 more
core +1 more source
Intracellular phase for an extracellular bacterial pathogen: MgtC shows the way
, 2015 Pseudomonas aeruginosa is an extracellular pathogen known to impair host phagocytic functions. However, our recent results identify MgtC as a novel actor in P.
Audrey Bernut +9 more
core +1 more source
An intracellular bacterial pathogen triggers RIG-I/MDA5-dependent necroptosis
Current Research in Microbial SciencesRIG-I and MDA5 are members of RIG-I-like receptors (RLRs) that detect viral RNA within the cytoplasm and subsequently initiate antiviral immune responses.
Hang Xu, Huili Li, Boguang Sun, Li Sun
doaj +1 more source
mBio, 2020 Chlamydia spp. productively infect mucosal epithelial cells of multiple anatomical sites, including the conjunctiva, lungs, gastrointestinal (GI) tract, and urogenital tract.
Sandra G. Morrison +5 more
doaj +1 more source
, 2008 BACKGROUND: Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium ...
Waddell, Simon +62 more
core +1 more source