Results 31 to 40 of about 6,113 (163)
Francisella novicida pathogenicity island encoded proteins were secreted during infection of macrophage-like cells. [PDF]
PLoS ONE, 2014 Intracellular pathogens and other organisms have evolved mechanisms to exploit host cells for their life cycles. Virulence genes of some intracellular bacteria responsible for these mechanisms are located in pathogenicity islands, such as secretion ...
Rebekah F Hare, Karsten Hueffer
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Increased Sensitivity of Amoeba-Grown Francisella Species to Disinfectants
, 2020 Francisella tularensis is a highly infectious, intracellular bacterium and it is the causative agent of tularemia. The bacterium has been isolated from more than 250 species, including protozoa.
Marečić, Valentina +17 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2010 The tularemia-causing bacterium Francisella tularensis is a facultative intracellular organism with a complex intracellular lifecycle that ensures its survival and proliferation in a variety of mammalian cell types, including professional phagocytes ...
Audrey eChong, Jean eCelli
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Characterization of the Francisella Virulence Factor RipA [PDF]
, 2009 Francisella tularensis is a highly virulent facultative intracellular pathogen; however, the mechanisms by which Francisella virulence factors mediate this virulence are not well defined.
Fuller, James Robertson
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Nlrp3 Increases the Host’s Susceptibility to Tularemia
Frontiers in Microbiology, 2021 Francisella tularensis (F. tularensis) is a Gram-negative, intracellular bacterium and the causative agent of a fatal human disease known as tularemia. The CDC has classified F.
Ragavan V. Suresh +7 more
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Francisella tularensis,Portugal
Emerging Infectious Diseases, 2007 To the Editor: Tularemia is a zoonosis caused by Francisella tularensis. Recently, tularemia has emerged in new locations, populations, and settings (1). After an outbreak in Spain in 1997 (2), it was expected that the disease would spread toward Portugal, a country with an extended area that borders the affected areas.
Isabel Lopes de Carvalho +5 more
openaire +3 more sources
Tularemia treatment: experimental and clinical data
Frontiers in MicrobiologyTularemia is a zoonosis caused by the Gram negative, facultative intracellular bacterium Francisella tularensis. This disease has multiple clinical presentations according to the route of infection, the virulence of the infecting bacterial strain, and ...
Max Maurin +10 more
doaj +1 more source
Presence of Francisella tularensis subsp. holarctica DNA in the Aquatic Environment in France
Microorganisms, 2021 In 2018, the incidence of tularemia increased twofold in the west of France, with many pneumonic forms, suggesting environmental sources of infection. We investigated the presence of Francisellatularensis subsp.
Camille D. Brunet +5 more
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Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source
, 2021 International audienceFrancisella tularensis is the causative agent of tularemia. Because of its extreme infectivity and high mortality rate, this pathogen was classified as a biothreat agent.
Barras, Frederic +8 more
core +1 more source