Results 51 to 60 of about 19,579 (213)

Galleria mellonella Reveals Niche Differences Between Highly Pathogenic and Closely Related Strains of Francisella spp.

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Francisella tularensis, a highly virulent bacteria that causes the zoonotic disease tularemia, is considered a potential agent of biological warfare and bioterrorism.
Johanna Thelaus   +4 more
doaj   +1 more source

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir   +6 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

Genome characterisation of the genus Francisella reveals insight into similar evolutionary paths in pathogens of mammals and fish

open access: yesBMC Genomics, 2012
Background Prior to this study, relatively few strains of Francisella had been genome-sequenced. Previously published Francisella genome sequences were largely restricted to the zoonotic agent F. tularensis.
Sjödin Andreas   +9 more
doaj   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

open access: yesIntegrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source

Francisella-like Endosymbionts of Ticks

open access: yesJournal of Invertebrate Pathology, 2000
Ticks affect human and animal health both directly by their blood feeding and indirectly by transmission of many disease-causing bacteria, such as Rickettsia, Ehrlichia, Borrelia, Coxiella, Cowdria, Anaplasma, Aegyptionella, and Tularemia, as well as many viruses (Piesman and Gage, 1996).
Sun, Ling V.   +3 more
openaire   +5 more sources

Drivers of Host–Pathogen Community Assemblages in European Forests and Urban Green Spaces

open access: yesIntegrative Zoology, EarlyView.
ABSTRACT Despite advances in understanding infectious diseases, the persistence and re‐emergence of wildlife pathogens continue to raise public and veterinary health concerns. This study investigates the relationship between biodiversity and rodent‐borne diseases in Europe, focusing on habitat alterations and their impact on rodent diversity.
Vincent Sluydts   +21 more
wiley   +1 more source

GlpT homologs identified in Francisella spp.

open access: yes, 2012
GlpT homologs identified in Francisella spp.
Emily R. Jackson (127580)   +8 more
core   +1 more source

UbiB proteins mediate an ATP‐dependent decarboxylation step in bacterial ubiquinone biosynthesis

open access: yesThe FEBS Journal, EarlyView.
UbiB proteins are atypical protein kinase‐like enzymes essential for ubiquinone biosynthesis. Here, we demonstrate that bacterial UbiB proteins catalyze the O2‐dependent decarboxylation of ubiquinone precursors, a process linked to their ATPase activity.
Katayoun Kazemzadeh   +12 more
wiley   +1 more source

Immunobiological Properties of Francisella tularensis 15/10 Strain with Deleted recA Gene

open access: yesПроблемы особо опасных инфекций, 2011
Deletion of recA gene in Francisella tularensis 15/10 genome leads to the increase in its sensitivity to ultraviolet irradiation, reduction of the homologous recombination capacity, and a slight decline of virulence for mice.
A. A. Lapin   +6 more
doaj   +1 more source

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