Results 61 to 70 of about 27,961 (205)

A galU mutant of francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia [PDF]

, 2011
Background A number of studies have revealed that Francisella tularensis (FT) suppresses innate immune responses such as chemokine/cytokine production and neutrophil recruitment in the lungs following pulmonary infection via an unidentified mechanism ...
Himangi R Jayakar, Jyothi Parvathareddy, Elizabeth A Fitzpatrick, Xiaowen R Bina, James E Bina, Fabio Re, Felicia D Emery, Mark A Miller   +7 more
core   +2 more sources

CRISPR/Cas Genome Editing and Its Applications in Cereal Crop Improvement

Plant-Environment Interactions, Volume 7, Issue 2, April 2026.
ABSTRACT CRISPR/Cas‐based genome editing has emerged as a transformative tool for precise genetic improvement of cereal crops. Recent advances in CRISPR technologies, including Cas9, Cas12, Cas13, base editing, and prime editing, have enabled targeted modification of genes and regulatory elements controlling yield, stress tolerance, and grain ...
Sirisha Kaniganti, Himanshu Saini, A. K. Chaitanya, Niranjan Hegde, Priya Shah, Nakul D. Magar, Ramesh Rijal, Jeevan Jyoti Kaushik, Deepak Nanda, Sharad Sachan, Anand Kumar, Roopali Bhoite, Harsha Rayudu Jamedar   +12 more
wiley   +1 more source

Immunobiological Properties of Francisella tularensis 15/10 Strain with Deleted recA Gene

Проблемы особо опасных инфекций, 2011
Deletion of recA gene in Francisella tularensis 15/10 genome leads to the increase in its sensitivity to ultraviolet irradiation, reduction of the homologous recombination capacity, and a slight decline of virulence for mice.
A. A. Lapin, A. N. Mokrievich, G. M. Vakhrameeva, T. I. Kombarova, I. V. Bakhteeva, I. A. Dyatlov, V. M. Pavlov   +6 more
doaj   +1 more source

Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]

, 2011
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle, Lieselotte eVande Walle, Mohamed eLamkanfi, Mohamed eLamkanfi   +3 more
core   +2 more sources

Francisella tularensis Bacteremia [PDF]

Journal of Clinical Microbiology, 2003
ABSTRACT Bacteremia caused by Francisella tularensis is rare and has been reported mainly in the United States and infrequently in Europe. We report herein the first case of bacteremic F. tularensis pneumonia in an immunocompetent individual in southern Europe.
X, Haristoy, A, Lozniewski, C, Tram, D, Simeon, L, Bevanger, C, Lion   +5 more
openaire   +2 more sources

Galectin‐9high Neutrophils Exacerbate Radiation‐Induced Frailty

Aging Cell, Volume 25, Issue 4, April 2026.
EccDNA shedding after skin radiation injury activates the JAK1/2‐STAT1 pathway in splenic GMP cells to induce the production of GAL‐9high neutrophils. This unique population of hyperactive GAL‐9high neutrophils is identified with characteristics of elevated NETs and IFN‐γ, etc.
Zhuo Cheng, Le Ma, Yan Chen, Jialun Li, Yali Dai, Wentao Xie, Yingjie Li, Tianlang Xu, Zhihe Hu, Weilin Huang, Jingyuan Zhou, Jie Wu, Long Chen, Chunmeng Shi   +13 more
wiley   +1 more source

First case of Francisella bacteraemia in Western Australia

New Microbes and New Infections, 2015
Francisella species are Gram-negative, nonmotile, pleomorphic coccobacilli, facultative intracellular fastidious bacteria. We report the isolation of a Francisella-like species from a blood culture collected from a 44-year-old bacteraemic patient in ...
Max Aravena-Román, Adam Merritt, Timothy J.J. Inglis   +2 more
doaj   +1 more source

COMPARATIVE STUDIES OF FRANCISELLA TULARENSIS AND FRANCISELLA NOVICIDA [PDF]

Journal of Bacteriology, 1964
Owen , C. R. (U.S. Public Health Service, Rocky Mountain Laboratory, Hamilton, Mont.), E. O. Buker, W. L. Jellison, D. B. Lackman, and J. F. Bell . Comparative studies of Francisella tularensis and Francisella novicida . J. Bacteriol. 87:
C R, OWEN, E O, BUKER, W L, JELLISON, D B, LACKMAN, J F, BELL   +4 more
openaire   +2 more sources

Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and is linked with type VI secretion and alterations to the host phagosomal membrane

mBio
Francisella tularensis is a gram-negative, intracellular pathogen that causes the zoonotic disease tularemia. Due to its ease of dissemination and high lethality, F.
Maheen Rashid, Shoichi Tachiyama, Shiwei Zhu, Hang Zhao, William D. McCaig, Jingchuan Sun, Huilin Li, Jun Liu, David G. Thanassi   +8 more
doaj   +1 more source

Monocyte / macrophage inflammatory response pathways to combat Francisella infection: possible therapeutic targets?

Frontiers in Cellular and Infection Microbiology, 2014
Francisella tularensis can bypass and suppress host immune responses, even to the point of manipulating immune cell phenotypes and intercellular inflammatory networks. Strengthening these responses such that immune cells more readily identify and destroy
Devyn D Gillette, Susheela eTridandapani, Jonathan P Butchar   +2 more
doaj   +1 more source