Results 21 to 30 of about 21,361 (224)

Immunobiological Properties of Francisella tularensis 15/10 Strain with Deleted recA Gene

Проблемы особо опасных инфекций, 2011
Deletion of recA gene in Francisella tularensis 15/10 genome leads to the increase in its sensitivity to ultraviolet irradiation, reduction of the homologous recombination capacity, and a slight decline of virulence for mice.
A. A. Lapin, A. N. Mokrievich, G. M. Vakhrameeva, T. I. Kombarova, I. V. Bakhteeva, I. A. Dyatlov, V. M. Pavlov   +6 more
doaj   +1 more source

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. [PDF]

, 2010
Francisella tularensis, the causative agent of tularemia, infects host macrophages, which triggers production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-18. We elucidate here how host macrophages recognize F.
Alnemri, Emad S, Datta, Pinaki, Eisenlohr, Laurence, Fernandes-Alnemri, Teresa, Huang, Lan, Juliana, Christine, Kang, Seokwon, Landel, Carlisle P, McCormick, Margaret, McDermott, Erin, Solorzano, Leobaldo, Wu, Jianghong, Yu, Je-Wook   +12 more
core   +3 more sources

TaqMan real-time PCR assays for single-nucleotide polymorphisms which identify Francisella tularensis and its subspecies and subpopulations. [PDF]

PLoS ONE, 2014
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into three subspecies and multiple subpopulations that differ in virulence and geographic distribution.
Dawn N Birdsell, Amy J Vogler, Jordan Buchhagen, Ashley Clare, Emily Kaufman, Amber Naumann, Elizabeth Driebe, David M Wagner, Paul S Keim   +8 more
doaj   +1 more source

Characterization of Francisella species isolated from the cooling water of an air conditioning system. [PDF]

, 2015
Strains of Francisella spp. were isolated from cooling water from an air conditioning system in Guangzhou, China. These strains are Gram negative, coccobacilli, non-motile, oxidase negative, catalase negative, esterase and lipid esterase positive.
Atwill, Edward, Chen, Shouyi, Gu, Quan, Hou, Shuiping, Li, Juntao, Li, Xunde, Qu, Pinghua   +6 more
core   +3 more sources

Assessment of Diagnostic Efficiency of PCR Kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF» when Analyzing Biological Samples from Animals with Experimental Tularemia

Проблемы особо опасных инфекций, 2016
Objective of the study is to assess diagnostic efficiency of PCR kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF», when performing analysis of biological samples from animals with experimental tularemia, as compared to other
A. M. Senichkina, N. A. Osina, A. S. Abdrashitova, V. G. Germanchuk   +3 more
doaj   +1 more source

Type VI secretion: a beginner's guide [PDF]

, 2008
Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Akeda, Baron, Bladergroen, Brzuszkiewicz, Christopher M Bailey, Dandekar, Das, Das, de Bruin, Dreyfus, Dudley, Dudley, Durocher, Economou, Finn, Folkesson, Gardy, Henderson, Johnson, Kulasekara, Lewis EH Bingle, Mark J Pallen, Mougous, Mougous, Nano, Pallen, Parsons, Pukatzki, Pukatzki, Purcell, Roest, Schell, Schlieker, Seshadri, Shalom, Sheahan, Srinivasa Rao, Tatusov, VanRheenen, Ventre, Wang, Weibezahn, Williams, Yahr, Yeo, Zheng, Zheng, Zusman   +47 more
core   +1 more source

Putting the Jigsaw Together - A Brief Insight Into the Tularemia

Open Life Sciences, 2015
Tularemia is a debilitating febrile and potentially fatal zoonotic disease of humans and other vertebrates caused by the Gram-negative bacterium Francisella tularensis. The natural reservoirs are small rodents, hares, and possibly amoebas in water.
Kubelkova K., Macela A.
doaj   +1 more source

The Subversion of the Immune System by Francisella Tularensis [PDF]

, 2011
Francisella tularensis is a highly virulent bacterial pathogen and the causative agent of tularemia. Perhaps the most impressive feature of this bacterium is its ability to cause lethal disease following inoculation of as few as 15 organisms.
Catharine M. Bosio
core   +1 more source

Global transcriptional response to mammalian temperature provides new insight into pathogenesis [PDF]

, 2008
Background After infecting a mammalian host, the facultative intracellular bacterium, Francisella tularensis, encounters an elevated environmental temperature.
Joseph Horzempa, Paul E Carlson, Dawn M O'Dee, Robert MQ Shanks, Gerard J Nau, J Ellis, A Sjostedt, DT Dennis, BP Berdal, PC Oyston, FE Nano, I Golovliov, K Deng, J Lenco, JT Sullivan, PE Carlson Jr, A Qin, J Su, DS Weiss, S Twine, JA Carroll, JF Miller, C Ojaimi, LM Smoot, T Tobe, CJ Hueck, U Zuber, DB Straus, ME Konkel, M Ericsson, M Ericsson, KL Meibom, NB Bhatnagar, SA Shaffer, NP Mohapatra, S Patel, SF Altschul, L Falquet, MJ Blaser, Z Xiang, MK Townsend, EB Nix, OM de Bruin, CD Herren, C Siatskas, MG Tozzi, K Hammer-Jespersen, RW Titball, A Sjostedt, CM Lauriano, A Brotcke, DL Clemens, A Ben Nasr, GS Schulert, A Balagopal, RE Chamberlain, TR Golub, S Rozen, J Horzempa, RM Shanks, I Golovliov, J Horzempa, PH Edelstein, JG Smedley 3rd, CM Robinson, SD Tachado, XH Lai, TM Maier, G Ruvkun, ED LoVullo, R Tempel, CG Gray, TM Maier, JC Charity   +73 more
core   +2 more sources

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources