Arthropod Infection Models for Francisella tularensis [PDF]
Purpose of Review Little is known about the interactions between Francisella tularensis and arthropods. The advent of next-generation sequencing led to a better knowledge of the genetic diversity of F.
Pilo, Paola, Paola Pilo
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Immunobiological Properties of Francisella tularensis 15/10 Strain with Deleted recA Gene
Deletion of recA gene in Francisella tularensis 15/10 genome leads to the increase in its sensitivity to ultraviolet irradiation, reduction of the homologous recombination capacity, and a slight decline of virulence for mice.
A. A. Lapin +6 more
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Francisella tularensis,Portugal
To the Editor: Tularemia is a zoonosis caused by Francisella tularensis. Recently, tularemia has emerged in new locations, populations, and settings (1). After an outbreak in Spain in 1997 (2), it was expected that the disease would spread toward Portugal, a country with an extended area that borders the affected areas.
Isabel Lopes de Carvalho +5 more
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TaqMan real-time PCR assays for single-nucleotide polymorphisms which identify Francisella tularensis and its subspecies and subpopulations. [PDF]
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into three subspecies and multiple subpopulations that differ in virulence and geographic distribution.
Dawn N Birdsell +8 more
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Identification of Francisella tularensis cluster in central and western Europe [PDF]
We conducted a molecular analysis of Francisella tularensis strains isolated in Switzerland and identified a specific subpopulation belonging to a cluster of F. tularensis subsp.
Joachim Frey +7 more
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Glycosylation of DsbA in Francisella tularensis subsp. tularensis [PDF]
ABSTRACTInFrancisella tularensissubsp.tularensis, DsbA has been shown to be an essential virulence factor and has been observed to migrate to multiple protein spots on two-dimensional electrophoresis gels. In this work, we show that the protein is modified with a 1,156-Da glycan moiety inO-linkage.
Thomas, Rebecca M. +10 more
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Putting the Jigsaw Together - A Brief Insight Into the Tularemia
Tularemia is a debilitating febrile and potentially fatal zoonotic disease of humans and other vertebrates caused by the Gram-negative bacterium Francisella tularensis. The natural reservoirs are small rodents, hares, and possibly amoebas in water.
Kubelkova K., Macela A.
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The Divergent Intracellular Lifestyle of Francisella tularensis in Evolutionarily Distinct Host Cells. [PDF]
Francisella tularensis isagram-negative,facultative, intracellular bacteriumthatsurvives in mammals, arthropods, and amoebae; however, macrophages are considered thekey cellsin pathogenesis oftularemia in mammals.
Mateja Ozanic +7 more
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An Unusual Case of Francisella tularensis
A 67-year-old male presented with complaints of weakness, fatigue, and shortness of breath in the context of a recent hospitalization for the same unresolved symptoms. After a largely nonspecific clinical presentation, a chest X-ray revealed a loculated pleural effusion.
Samantha Huang +3 more
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Natural Infection of a European Red Squirrel (Sciurus vulgaris) with Francisella tularensis subsp. holarctica. [PDF]
Postmortem examination and immunohistochemical and bacteriologic analyses on a free-ranging European red squirrel (Sciurus vulgaris) revealed a systemic infection with Francisella tularensis.
Kittl, Sonja +4 more
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