Results 11 to 20 of about 21,361 (224)
Genetic Manipulation of Francisella Tularensis [PDF]
Frontiers in Microbiology, 2011 Francisella tularensis is a facultative intracellular pathogen that causes the disease tularemia. F. tularensis subsp. tularensis causes the most severe disease in humans and has been classified as a select A agent and potential bioweapon.
Xhavit Zogaj, Karl E. Klose
core +6 more sources
De Novo Design of High-Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor. [PDF]
Angew Chem Int Ed EnglHybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gokce-Alpkilic G +18 more
europepmc +3 more sources
Francisella tularensis Subspecies holarctica and Tularemia in Germany
Microorganisms, 2020 Tularemia is a zoonotic disease caused by Francisella tularensis a small, pleomorphic, facultative intracellular bacterium. In Europe, infections in animals and humans are caused mainly by Francisella tularensis subspecies holarctica.
Sandra Appelt +5 more
doaj +1 more source
Early infection-induced natural antibody response
Scientific Reports, 2021 There remains to this day a great gap in understanding as to the role of B cells and their products—antibodies and cytokines—in mediating the protective response to Francisella tularensis, a Gram-negative coccobacillus belonging to the group of ...
Klara Kubelkova +4 more
doaj +1 more source
Molecular epidemiology of tick-borne pathogens along Hexi Corridor of Gansu Province
Di-san junyi daxue xuebao, 2021 Objective To investigate the possible tick-borne pathogens along the Hexi Corridor of Gansu Province. Methods Ticks were collected from animal surfaces, residents' livestock barns and by dragging a cloth over vegetation, and brought back alive to our ...
ZHANG Fang, WANG Xiaoheng
doaj +1 more source
Human tularemia in Italy. Is it a re-emerging disease? [PDF]
, 2014 In order to evaluate whether tularemia is re-emerging in Italy, data on mortality and morbidity (obtained by the National Institute of Statistics; ISTAT), Italian cases described in the scientific literature and data concerning hospitalizations for ...
A., Bella +4 more
core +1 more source
Francisella tularensis,Portugal
Emerging Infectious Diseases, 2007 To the Editor: Tularemia is a zoonosis caused by Francisella tularensis. Recently, tularemia has emerged in new locations, populations, and settings (1). After an outbreak in Spain in 1997 (2), it was expected that the disease would spread toward Portugal, a country with an extended area that borders the affected areas.
Isabel Lopes de Carvalho +5 more
openaire +3 more sources
Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida. [PDF]
PLoS ONE, 2016 Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s) behind ...
Siva T Sarva +3 more
doaj +1 more source
Density-Dependent Prevalence of Francisella tularensis in Fluctuating Vole Populations, Northwestern Spain [PDF]
, 2017 Self Archiving; https://wwwnc.cdc.gov/eid/page/copyright-and-disclaimers J.J.L.L., F.M., and R.R.P. held official licenses for trapping wildlife in Spain. Capture permits were provided by the Dirección General del Medio Natural, Junta de Castilla y León.
Anda, Pedro +9 more
core +4 more sources
Regulation of virulence in Francisella tularensis by small non-coding RNAs [PDF]
, 2011 Using a cDNA cloning and sequencing approach we have shown that Francisella tularensis expresses homologues of several small RNAs (sRNAs) that are well-conserved among diverse bacteria.
Alain Charbit +6 more
core +2 more sources