Results 31 to 40 of about 6,408 (161)

Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella species.

PLoS ONE, 2013
Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms.
Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Dana P Scott, Catharine M Bosio   +4 more
doaj   +1 more source

The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens. [PDF]

, 2006
We have determined the sequence of the gene cluster encoding the O antigen in Francisella novicida and compared it to the previously reported O-antigen cluster in Francisella tularensis subsp. tularensis.
Richard W. Titball, C. F. Oyston, Petra, L. Prior, Joann, Wilson, Jennifer C, Wilson, Jenny, Emma Waters, I. Darren Grice, Hitchen, Paul, Kate Griffin, Hitchen, Paul G, Jennifer C. Wilson, Thomas, Rebecca, Waters, Emma, Stephen L. Michell, Grice, I Darren, Oyston, Petra CF, Michell, Stephen L, Thomas, Rebecca M, Prior, Joann L, Petra C. F. Oyston, Titball, Richard, Titball, Richard W, Grice, Darren, Rebecca M. Thomas, Paul G. Hitchen, Griffin, Kate, Joann L. Prior, L. Michell, Stephen   +27 more
core   +1 more source

Genomic characterization of Francisella tularensis and other diverse Francisella species from complex samples.

PLoS ONE, 2022
Francisella tularensis, the bacterium that causes the zoonosis tularemia, and its genetic near neighbor species, can be difficult or impossible to cultivate from complex samples.
David M Wagner, Dawn N Birdsell, Ryelan F McDonough, Roxanne Nottingham, Karisma Kocos, Kimberly Celona, Yasemin Özsürekci, Caroline Öhrman, Linda Karlsson, Kerstin Myrtennäs, Andreas Sjödin, Anders Johansson, Paul S Keim, Mats Forsman, Jason W Sahl   +14 more
doaj   +2 more sources

Tularemia treatment: experimental and clinical data

Frontiers in Microbiology
Tularemia is a zoonosis caused by the Gram negative, facultative intracellular bacterium Francisella tularensis. This disease has multiple clinical presentations according to the route of infection, the virulence of the infecting bacterial strain, and ...
Max Maurin, Max Maurin, Léa Pondérand, Léa Pondérand, Aurélie Hennebique, Aurélie Hennebique, Isabelle Pelloux, Sandrine Boisset, Sandrine Boisset, Yvan Caspar, Yvan Caspar   +10 more
doaj   +1 more source

Revisiting Francisella tularensis subsp. holarctica, Causative Agent of Tularemia in Germany With Bioinformatics: New Insights in Genome Structure, DNA Methylation and Comparative Phylogenetic Analysis

Frontiers in Microbiology, 2018
Francisella (F.) tularensis is a highly virulent, Gram-negative bacterial pathogen and the causative agent of the zoonotic disease tularemia. Here, we generated, analyzed and characterized a high quality circular genome sequence of the F.
Anne Busch, Prasad Thomas, Eric Zuchantke, Holger Brendebach, Kerstin Neubert, Josephine Gruetzke, Sascha Al Dahouk, Martin Peters, Helmut Hotzel, Heinrich Neubauer, Herbert Tomaso   +10 more
doaj   +1 more source

First European report of Francisella tularensis subsp. holarctica isolation from a domestic cat [PDF]

, 2020
Francisella tularensis subsp. holarctica is a select agent causing life-threatening tularemia. It has been isolated from humans and animals, mainly lagomorphs and rodents, rarely other wild carnivore species.
Francey, Thierry, Kittl, Sonja, Jores, Joerg, Borel, Stéphanie, Brodard, Isabelle, Origgi, Francesco C., Ryser-Degiorgis, Marie-Pierre, Schweighauser, Ariane   +7 more
core   +2 more sources

Non-vaccinal prophylaxis of tularemia

Frontiers in Microbiology
Tularemia is a re-emerging zoonosis in many endemic countries. It is caused by Francisella tularensis, a gram-negative bacterium and biological threat agent.
Max Maurin, Max Maurin, Aurélie Hennebique, Aurélie Hennebique, Camille Brunet, Léa Pondérand, Léa Pondérand, Isabelle Pelloux, Sandrine Boisset, Sandrine Boisset, Yvan Caspar, Yvan Caspar   +11 more
doaj   +1 more source

Nutritional virulence of Francisella tularensis [PDF]

Frontiers in Cellular and Infection Microbiology, 2013
One of the mostfundamental aspects of infectious diseases is microbial acquisition of nutrients in vivo, which impacts virulence and antibiotic treatment.This article is focused on nutritional virulence of F.tularensis.
Šantić, Marina, Abu Kwaik, Yousef
openaire   +5 more sources

Rapid dissemination of Francisella tularensis and the effect of route of infection

BMC Microbiology, 2008
Background Francisella tularensis subsp. tularensis is classified as a Category A bioweapon that is capable of establishing a lethal infection in humans upon inhalation of very few organisms.
Jerabek Paul A, Morris Elizabeth G, Li Qun, Chang Tingtung A, Mares Chris A, Wang Zheng J, Ojeda Sandra S, Teale Judy M   +7 more
doaj   +1 more source

Francisella tularensis subsp. holarctica bacteraemia in an immunocompetent male

Respiratory Medicine Case Reports, 2023
Tularemia is a rare zoonotic disease caused by the two predominant subspecies of Francisella tularensis, namely subspecies tularensis and subspecies holarctica.
Niels Schepens, Thessa Verniest, Isabel Verstreken, Liesbet Henckaerts   +3 more
doaj   +1 more source