Results 31 to 40 of about 21,361 (224)

Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella species.

PLoS ONE, 2013
Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms.
Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Dana P Scott, Catharine M Bosio   +4 more
doaj   +1 more source

Francisella tularensis Bacteremia [PDF]

Journal of Clinical Microbiology, 2003
ABSTRACT Bacteremia caused by Francisella tularensis is rare and has been reported mainly in the United States and infrequently in Europe. We report herein the first case of bacteremic F. tularensis pneumonia in an immunocompetent individual in southern Europe.
X, Haristoy, A, Lozniewski, C, Tram, D, Simeon, L, Bevanger, C, Lion   +5 more
openaire   +2 more sources

A human macrophage – hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica [PDF]

, 2016
Detection of intracellular LPS in macrophage / hepatocyte co-cultures infected with LVS (open bars), spp. holarctica (grey filled bars) or spp. mediasiatica (black filled bars) and untreated control (hatched bars).
Alexander S. Mosig, Harald Funke, Herbert Tomaso, Knut Rennert, Otmar Huber, Peter Otto   +5 more
core   +3 more sources

Francisella tularensisvaccines [PDF]

FEMS Immunology & Medical Microbiology, 2007
Francisella tularensis is the causative agent of tularaemia, a disease which occurs naturally in some countries in the northern hemisphere. Recently, there has been a high level of interest in devising vaccines against the bacterium because of the potential for it to be used as a bioterrorism agent.
Kate F, Griffin, Petra C F, Oyston, Richard W, Titball   +2 more
openaire   +2 more sources

Tularemia treatment: experimental and clinical data

Frontiers in Microbiology
Tularemia is a zoonosis caused by the Gram negative, facultative intracellular bacterium Francisella tularensis. This disease has multiple clinical presentations according to the route of infection, the virulence of the infecting bacterial strain, and ...
Max Maurin, Max Maurin, Léa Pondérand, Léa Pondérand, Aurélie Hennebique, Aurélie Hennebique, Isabelle Pelloux, Sandrine Boisset, Sandrine Boisset, Yvan Caspar, Yvan Caspar   +10 more
doaj   +1 more source

Revisiting Francisella tularensis subsp. holarctica, Causative Agent of Tularemia in Germany With Bioinformatics: New Insights in Genome Structure, DNA Methylation and Comparative Phylogenetic Analysis

Frontiers in Microbiology, 2018
Francisella (F.) tularensis is a highly virulent, Gram-negative bacterial pathogen and the causative agent of the zoonotic disease tularemia. Here, we generated, analyzed and characterized a high quality circular genome sequence of the F.
Anne Busch, Prasad Thomas, Eric Zuchantke, Holger Brendebach, Kerstin Neubert, Josephine Gruetzke, Sascha Al Dahouk, Martin Peters, Helmut Hotzel, Heinrich Neubauer, Herbert Tomaso   +10 more
doaj   +1 more source

Francisella-like endosymbiont in Dermacentor reticulatus collected in Portugal [PDF]

, 2011
In Portugal, recent studies have confirmed the presence of Francisella tularensis in Dermacentor reticulatus. Bacterial endosymbionts with significant homology to F. tularensis have been described in several species of ticks.
Lopes de Carvalho, Isabel, Núncio, Maria Sofia, Santos, Nuno, Soares, Teresa, Zé-Zé, Líbia   +4 more
core   +1 more source

Genomic characterization of Francisella tularensis and other diverse Francisella species from complex samples

PLoS ONE, 2022
Francisella tularensis, the bacterium that causes the zoonosis tularemia, and its genetic near neighbor species, can be difficult or impossible to cultivate from complex samples.
David M. Wagner, Dawn N. Birdsell, Ryelan F. McDonough, Roxanne Nottingham, Karisma Kocos, Kimberly Celona, Yasemin Özsürekci, Caroline Öhrman, Linda Karlsson, Kerstin Myrtennäs, Andreas Sjödin, Anders Johansson, Paul S. Keim, Mats Forsman, Jason W. Sahl   +14 more
doaj   +2 more sources

Non-vaccinal prophylaxis of tularemia

Frontiers in Microbiology
Tularemia is a re-emerging zoonosis in many endemic countries. It is caused by Francisella tularensis, a gram-negative bacterium and biological threat agent.
Max Maurin, Max Maurin, Aurélie Hennebique, Aurélie Hennebique, Camille Brunet, Léa Pondérand, Léa Pondérand, Isabelle Pelloux, Sandrine Boisset, Sandrine Boisset, Yvan Caspar, Yvan Caspar   +11 more
doaj   +1 more source

Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensis [PDF]

, 2011
Francisella tularensis is a category A select agent based on its infectivity and virulence but disease mechanisms in infection remain poorly understood. Murine pulmonary models of infection were therefore employed to assess and compare dissemination and ...
Alan R. Schenkel, Andersson, Andersson, Andersson, Benoit, Bosio, Bosio, Butchar, Chase, Chiavolini, Chocarro, Cole, Conlan, Cremer, Dennis, Dennis, Edwin, Eisen, Elkins, England, Fortier, Gonzalez-Juarrero, Han, Helle Bielefeldt-Ohmann, Huang da, Jia, Keim, Lennon-Duménil, Liu, Luhrmann, Luke C. Kingry, Mahawar, Metzger, Moe, Ng, Nicole L. Marlenee, Ortaldo, Pechous, Petersen, Qin, Richard A. Bowen, Richard A. Slayden, Ryan M. Troyer, Sawyer, Sjostedt, Steven W. Dow, Troyer, Twine, Twine, Voth, Westgaard, Wilson, Woolard, Woolard   +53 more
core   +1 more source