Rombencephalitis Caused by Francisella tularensis [PDF]
ABSTRACT Common presentations of tularemia include pneumonia and ulceroglandular, oropharyngeal, or typhoidal disease. Neuromeningeal involvement is extremely rare. We report a case of a severe rhombencephalitis due to Francisella tularensis .
Barbaz, Mathilde +7 more
openaire +3 more sources
Rapid dissemination of
Background Francisella tularensis subsp. tularensis is classified as a Category A bioweapon that is capable of establishing a lethal infection in humans upon inhalation of very few organisms.
Jerabek Paul A +7 more
doaj +1 more source
Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains [PDF]
BACKGROUND: Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause disease. To uncover the factors that allow subspecies tularensis and holarctica to
Laurence Rohmer +34 more
core +1 more source
Phylogeography of Francisella tularensis subspecies holarctica from the country of Georgia [PDF]
Background Francisella tularensis, the causative agent of tularemia, displays subspecies-specific differences in virulence, geographic distribution, and genetic diversity. F. tularensis subsp.
Gvantsa Chanturia +21 more
core +1 more source
Francisella tularensis Transmission by Solid Organ Transplantation, 20171. [PDF]
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Annambhotla, Pallavi +28 more
core
Genetic Sequence Matching Using D4M Big Data Approaches
Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run.
Dodson, Stephanie +2 more
core +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
Exploitation of Host Cell Biology and Evasion of Immunity by Francisella Tularensis [PDF]
Francisella tularensis is an intracellular bacterium that infects humans and many small mammals. During infection, F. tularensis replicates predominantly in macrophages but also proliferate in other cell types. Entry into host cells is mediate by various
Rexford Asare, Yousef Abu Kwaik
core +1 more source
Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley +1 more source
Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008 [PDF]
Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable ...
Allue +34 more
core +1 more source

