Results 41 to 50 of about 13,693 (208)

TaqMan real-time PCR assays for single-nucleotide polymorphisms which identify Francisella tularensis and its subspecies and subpopulations. [PDF]

PLoS ONE, 2014
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into three subspecies and multiple subpopulations that differ in virulence and geographic distribution.
Dawn N Birdsell, Amy J Vogler, Jordan Buchhagen, Ashley Clare, Emily Kaufman, Amber Naumann, Elizabeth Driebe, David M Wagner, Paul S Keim   +8 more
doaj   +1 more source

Putting the Jigsaw Together - A Brief Insight Into the Tularemia

Open Life Sciences, 2015
Tularemia is a debilitating febrile and potentially fatal zoonotic disease of humans and other vertebrates caused by the Gram-negative bacterium Francisella tularensis. The natural reservoirs are small rodents, hares, and possibly amoebas in water.
Kubelkova K., Macela A.
doaj   +1 more source

An Unusual Case of Francisella tularensis

Case Reports in Infectious Diseases, 2022
A 67-year-old male presented with complaints of weakness, fatigue, and shortness of breath in the context of a recent hospitalization for the same unresolved symptoms. After a largely nonspecific clinical presentation, a chest X-ray revealed a loculated pleural effusion.
Samantha Huang, Bradley Kaptur, Julius Manu, Elias Woldegabriel   +3 more
openaire   +3 more sources

Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella species.

PLoS ONE, 2013
Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms.
Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Dana P Scott, Catharine M Bosio   +4 more
doaj   +1 more source

Glycosylation of DsbA in Francisella tularensis subsp. tularensis [PDF]

Journal of Bacteriology, 2011
ABSTRACTInFrancisella tularensissubsp.tularensis, DsbA has been shown to be an essential virulence factor and has been observed to migrate to multiple protein spots on two-dimensional electrophoresis gels. In this work, we show that the protein is modified with a 1,156-Da glycan moiety inO-linkage.
Thomas, Rebecca M., Twine, Susan M., Fulton, Kelly M., Tessier, Luc, Kilmury, Sara L. N., Ding, Wen, Harmer, Nicholas, Michell, Stephen L., Oyston, Petra C. F., Titball, Richard W., Prior, Joann L.   +10 more
openaire   +3 more sources

Francisella tularensis infection in a stone marten (Martes foina) without classic pathological lesions consistent with tularemia. [PDF]

, 2013
The current report describes the isolation and typing of a strain of Francisella tularensis, the causative agent of tularemia, from the spleen of a stone marten (Martes foina) showing no classic lesions consistent with the disease.
Origgi, Francesco, Wu, Natacha, Pilo, Paola, Francesco C. Origgi, Paola Pilo, Natacha Wu   +5 more
core   +1 more source

Genomic characterization of Francisella tularensis and other diverse Francisella species from complex samples.

PLoS ONE, 2022
Francisella tularensis, the bacterium that causes the zoonosis tularemia, and its genetic near neighbor species, can be difficult or impossible to cultivate from complex samples.
David M Wagner, Dawn N Birdsell, Ryelan F McDonough, Roxanne Nottingham, Karisma Kocos, Kimberly Celona, Yasemin Özsürekci, Caroline Öhrman, Linda Karlsson, Kerstin Myrtennäs, Andreas Sjödin, Anders Johansson, Paul S Keim, Mats Forsman, Jason W Sahl   +14 more
doaj   +2 more sources

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Tularemia treatment: experimental and clinical data

Frontiers in Microbiology
Tularemia is a zoonosis caused by the Gram negative, facultative intracellular bacterium Francisella tularensis. This disease has multiple clinical presentations according to the route of infection, the virulence of the infecting bacterial strain, and ...
Max Maurin, Max Maurin, Léa Pondérand, Léa Pondérand, Aurélie Hennebique, Aurélie Hennebique, Isabelle Pelloux, Sandrine Boisset, Sandrine Boisset, Yvan Caspar, Yvan Caspar   +10 more
doaj   +1 more source

Revisiting Francisella tularensis subsp. holarctica, Causative Agent of Tularemia in Germany With Bioinformatics: New Insights in Genome Structure, DNA Methylation and Comparative Phylogenetic Analysis

Frontiers in Microbiology, 2018
Francisella (F.) tularensis is a highly virulent, Gram-negative bacterial pathogen and the causative agent of the zoonotic disease tularemia. Here, we generated, analyzed and characterized a high quality circular genome sequence of the F.
Anne Busch, Prasad Thomas, Eric Zuchantke, Holger Brendebach, Kerstin Neubert, Josephine Gruetzke, Sascha Al Dahouk, Martin Peters, Helmut Hotzel, Heinrich Neubauer, Herbert Tomaso   +10 more
doaj   +1 more source