Results 61 to 70 of about 21,361 (224)

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

open access: yesThe FEBS Journal, Volume 293, Issue 3, Page 781-805, February 2026.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Immunogenic Properties of Cell Wall Preparations of Francisella tularensis Different Subspecies in Experimental Tularemia

open access: yesЭпидемиология и вакцинопрофилактика, 2018
Immunogenic properties of cell wall (CW) preparations of Francisella tularensis four subspecies are investigated. It is shown that the  preparations from F. tularensis urea lysates are not toxic for  experimental animals. Besides, CW of F.
A. V. Korneva   +9 more
doaj   +1 more source

Francisella and tularemia in western Asia, Iran: a systematic review

open access: yesNew Microbes and New Infections, 2023
Tularemia or rabbit fever is a transmissible disease from animals, rodents, and insects to human populations that is caused by Francisella tularensis. Epidemiological studies showed that tularemia is endemic throughout most different regions of the world.
Zahra Fooladfar, Farhad Moradi
doaj   +1 more source

Identification of small RNAs in Francisella tularensis [PDF]

open access: yes, 2010
Background: Regulation of bacterial gene expression by small RNAs (sRNAs) have proved to be important for many biological processes. Francisella tularensis is a highly pathogenic Gram-negative bacterium that causes the disease tularaemia in humans and ...
Alain Charbit   +6 more
core   +3 more sources

Glycosylation of DsbA in Francisella tularensis subsp. tularensis [PDF]

open access: yesJournal of Bacteriology, 2011
ABSTRACTInFrancisella tularensissubsp.tularensis, DsbA has been shown to be an essential virulence factor and has been observed to migrate to multiple protein spots on two-dimensional electrophoresis gels. In this work, we show that the protein is modified with a 1,156-Da glycan moiety inO-linkage.
Thomas, Rebecca M.   +10 more
openaire   +3 more sources

Molecular Screening of Black Flies (Diptera: Simuliidae) for Vector‐Borne Zoonotic Pathogens, South Moravia, Czech Republic

open access: yesZoonoses and Public Health, Volume 73, Issue 1, Page 95-106, February 2026.
ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Silvie Šikutová   +10 more
wiley   +1 more source

AR-13, a Celecoxib Derivative, Directly Kills Francisella In Vitro and Aids Clearance and Mouse Survival In Vivo

open access: yesFrontiers in Microbiology, 2017
Francisella tularensis (F. tularensis) is the causative agent of tularemia and is classified as a Tier 1 select agent. No licensed vaccine is currently available in the United States and treatment of tularemia is confined to few antibiotics.
Ky V. Hoang   +8 more
doaj   +1 more source

Francisella tularensis Schu S4 lipopolysaccharide core sugar and o-antigen mutants are attenuated in a mouse model of tularemia [PDF]

open access: yes, 2014
The virulence factors mediating Francisella pathogenesis are being investigated, with an emphasis on understanding how the organism evades innate immunity mechanisms.
Apicella, Michael A   +6 more
core   +2 more sources

Nutritional virulence of Francisella tularensis [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2013
One of the mostfundamental aspects of infectious diseases is microbial acquisition of nutrients in vivo, which impacts virulence and antibiotic treatment.This article is focused on nutritional virulence of F.tularensis.
Šantić, Marina, Abu Kwaik, Yousef
openaire   +4 more sources

Exploiting Lactic Acid Bacteria for Regulating Autophagy to Improve Health in Foods and Supplements: A Recent Update

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Lactic acid bacteria (LAB) are frequently used as health supplements. They enhance digestion, regulate immunity, improve gut microbiota, and prevent and manage diseases. Autophagy has a crucial role in the prevention and treatment of tumors, cardiovascular diseases, and pathogenic infections.
Yang Chen   +8 more
wiley   +1 more source

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