Results 61 to 70 of about 13,693 (208)
Putting Rodents at the Center of One Health Programs: A Narrative Synthesis
Integrative Zoology, EarlyView.Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley +1 more source
Ecological Niche Modeling of Francisella tularensis Subspecies and Clades in the United States
, 2010 Two subspecies of Francisella tularensis are recognized: F. tularensis subsp. tularensis (type A) and F. tularensis subsp. holartica (type B). Type A has been subdivided further into A1a, A1b, and A2, which differ geographically and clinically.
Kugelar, Kiersten +5 more
core +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
MedComm, Volume 7, Issue 5, May 2026.Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis
, 2010 Francisella tularensis induces apoptosis within macrophages but the temporal and spatial modulation through activation of caspase-1, caspase-3, and the anti-apoptosis nuclear transcription factor B (NF-kappaB) is not known. Whether escape of the bacteria
Asare, Rexford +4 more
core +1 more source
mBio, 2022 Francisella tularensis, a Tier 1 select agent of bioterrorism, contains a type VI secretion system (T6SS) encoded within the Francisella pathogenicity island (FPI), which is critical for its pathogenesis.
Xiaoyu Liu +5 more
doaj +1 more source
Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT Water pollution is becoming increasingly severe, posing a serious hazard to human health and ecological security. Therefore, it is necessary to develop rapid, sensitive, and universal analytical methods to detect residual pollutants in actual water.
Yi Xing +4 more
wiley +1 more source
Francisella tularensisvaccines [PDF]
FEMS Immunology & Medical Microbiology, 2007 Francisella tularensis is the causative agent of tularaemia, a disease which occurs naturally in some countries in the northern hemisphere. Recently, there has been a high level of interest in devising vaccines against the bacterium because of the potential for it to be used as a bioterrorism agent.
Kate F, Griffin +2 more
openaire +2 more sources
, 2015 Francisella tularensis isagram-negative,facultative, intracellular bacteriumthatsurvives in mammals, arthropods, and amoebae; however, macrophages are considered thekey cellsin pathogenesis oftularemia in mammals.
Mateja Ozanic +7 more
core +1 more source
BMC Genomics, 2012 Background Prior to this study, relatively few strains of Francisella had been genome-sequenced. Previously published Francisella genome sequences were largely restricted to the zoonotic agent F. tularensis.
Sjödin Andreas +9 more
doaj +1 more source
Modified activities of macrophages’ deubiquitinating enzymes after Francisella infection
Frontiers in Immunology, 2023 Francisella tularensis influences several host molecular/signaling pathways during infection. Ubiquitination and deubiquitination are among the most important regulatory mechanisms and respectively occur through attachment or removal of the ubiquitin ...
Vera Vozandychova +8 more
doaj +1 more source