Results 51 to 60 of about 6,408 (161)

Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Katie C. Sprinkel, Annika R. Geiger, Monique L. van Hoek   +2 more
wiley   +1 more source

Invasion of Erythrocytes by Francisella tularensis [PDF]

The Journal of Infectious Diseases, 2011
Francisella tularensis is the causative agent of tularemia and is classified as a category A biodefense agent by the Centers for Disease Control and Prevention because of its highly infectious nature. F. tularensis infects leukocytes and exhibits an extracellular phase in the blood of the host. It is unknown, however, whether F.
Joseph, Horzempa, Dawn M, O'Dee, Donna Beer, Stolz, Jonathan M, Franks, Doris, Clay, Gerard J, Nau   +5 more
openaire   +2 more sources

Study of the UV Irradiation and Nalidicsic Acid Effect on the RecA-protein Induction in Francisella tularensis 15/10 Cells

Проблемы особо опасных инфекций, 2011
Studied is the UV irradiation and nalidicsic acid effect on the RecA-protein synthesis in Francisella tularensis 15/10 cells. Obtained is the specific murine serum to the recombinant RecA-protein.
A. A. Lapin, T. B. Kravchenko, A. N. Mokrievich, G. M. Vakhrameeva, T. I. Kombarova, I. A. Dyatlov, V. M. Pavlov   +6 more
doaj   +1 more source

Modified activities of macrophages’ deubiquitinating enzymes after Francisella infection

Frontiers in Immunology, 2023
Francisella tularensis influences several host molecular/signaling pathways during infection. Ubiquitination and deubiquitination are among the most important regulatory mechanisms and respectively occur through attachment or removal of the ubiquitin ...
Vera Vozandychova, Pavel Rehulka, Kamil Hercik, Kamil Hercik, Petra Spidlova, Pavla Pavlik, Jaroslav Hanus, Romana Hadravova, Jiri Stulik   +8 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Francisella tularensisvaccines [PDF]

FEMS Immunology & Medical Microbiology, 2007
Francisella tularensis is the causative agent of tularaemia, a disease which occurs naturally in some countries in the northern hemisphere. Recently, there has been a high level of interest in devising vaccines against the bacterium because of the potential for it to be used as a bioterrorism agent.
Kate F, Griffin, Petra C F, Oyston, Richard W, Titball   +2 more
openaire   +2 more sources

Különböző eredetű Francisella tularensis törzsek összehasonlító vizsgálata = Comparative examination of Francisella tularensis strains isolated from different species in Hungary [PDF]

, 2012
Vizsgálataink során Magyarország közel 30 településéről összesen 67 Francisella tularensis törzset gyűjtöttünk, amely révén létrehoztunk egy hazai F. tularensis törzsgyűjteményt.
Makrai, László
core   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, Volume 199, Issue 5, Page e238-e249, 5/12 September 2026.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source

Ecology, host and vectors of Francisella tularensis [PDF]

, 2009
Francisella tularensis aerobna je, nesporogena, gram-negativna fakultativna unutarstanična bakterija koja u ljudi i životinja uzrokuje smrtonosnu bolest tularemiju.
Semić, Vildana, Lazarić, Iva, Brezovec, Martin, Šantić, Marina   +3 more
core   +5 more sources

Immunogenic Properties of Cell Wall Preparations of Francisella tularensis Different Subspecies in Experimental Tularemia

Эпидемиология и вакцинопрофилактика, 2018
Immunogenic properties of cell wall (CW) preparations of Francisella tularensis four subspecies are investigated. It is shown that the  preparations from F. tularensis urea lysates are not toxic for  experimental animals. Besides, CW of F.
A. V. Korneva, V. B. Nikolaev, T. A. Ivanova, V. I. Dubrovina, G. B. Mukhturgin, E. Yu. Markov, T. P. Starovoitova, A. V. Mazepa, T. T. Shkaruba, S. V. Balakhonov   +9 more
doaj   +1 more source