Results 51 to 60 of about 21,361 (224)

Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies.

PLoS Pathogens, 2009
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis.
Mia D Champion, Qiandong Zeng, Eli B Nix, Francis E Nano, Paul Keim, Chinnappa D Kodira, Mark Borowsky, Sarah Young, Michael Koehrsen, Reinhard Engels, Matthew Pearson, Clint Howarth, Lisa Larson, Jared White, Lucia Alvarado, Mats Forsman, Scott W Bearden, Anders Sjöstedt, Richard Titball, Stephen L Michell, Bruce Birren, James Galagan   +21 more
doaj   +1 more source

Modified activities of macrophages’ deubiquitinating enzymes after Francisella infection

Frontiers in Immunology, 2023
Francisella tularensis influences several host molecular/signaling pathways during infection. Ubiquitination and deubiquitination are among the most important regulatory mechanisms and respectively occur through attachment or removal of the ubiquitin ...
Vera Vozandychova, Pavel Rehulka, Kamil Hercik, Kamil Hercik, Petra Spidlova, Pavla Pavlik, Jaroslav Hanus, Romana Hadravova, Jiri Stulik   +8 more
doaj   +1 more source

A galU mutant of francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia [PDF]

, 2011
Background A number of studies have revealed that Francisella tularensis (FT) suppresses innate immune responses such as chemokine/cytokine production and neutrophil recruitment in the lungs following pulmonary infection via an unidentified mechanism ...
Himangi R Jayakar, Jyothi Parvathareddy, Elizabeth A Fitzpatrick, Xiaowen R Bina, James E Bina, Fabio Re, Felicia D Emery, Mark A Miller   +7 more
core   +2 more sources

Genome characterisation of the genus Francisella reveals insight into similar evolutionary paths in pathogens of mammals and fish

BMC Genomics, 2012
Background Prior to this study, relatively few strains of Francisella had been genome-sequenced. Previously published Francisella genome sequences were largely restricted to the zoonotic agent F. tularensis.
Sjödin Andreas, Svensson Kerstin, Öhrman Caroline, Ahlinder Jon, Lindgren Petter, Duodu Samuel, Johansson Anders, Colquhoun Duncan J, Larsson Pär, Forsman Mats   +9 more
doaj   +1 more source

Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System

mBio, 2022
Francisella tularensis, a Tier 1 select agent of bioterrorism, contains a type VI secretion system (T6SS) encoded within the Francisella pathogenicity island (FPI), which is critical for its pathogenesis.
Xiaoyu Liu, Daniel L. Clemens, Bai-Yu Lee, Xue Yang, Z. Hong Zhou, Marcus A. Horwitz   +5 more
doaj   +1 more source

Különböző eredetű Francisella tularensis törzsek összehasonlító vizsgálata = Comparative examination of Francisella tularensis strains isolated from different species in Hungary [PDF]

, 2012
Vizsgálataink során Magyarország közel 30 településéről összesen 67 Francisella tularensis törzset gyűjtöttünk, amely révén létrehoztunk egy hazai F. tularensis törzsgyűjteményt.
Makrai, László
core  

Enhanced survival but not amplification of Francisella spp. in the presence of free-living amoebae [PDF]

, 2016
Transmission of Francisella tularensis, the etiologic agent of tularemia, has been associated with various water sources. Survival of many waterborne pathogens within free-living amoeba (FLA) is well documented; however, the role of amoebae in the ...
Buse, Helen Y., Rice, Eugene W., Schaefer III, Frank W.   +2 more
core   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, Volume 13, Issue 10, 18 February 2026.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Study of the UV Irradiation and Nalidicsic Acid Effect on the RecA-protein Induction in Francisella tularensis 15/10 Cells

Проблемы особо опасных инфекций, 2011
Studied is the UV irradiation and nalidicsic acid effect on the RecA-protein synthesis in Francisella tularensis 15/10 cells. Obtained is the specific murine serum to the recombinant RecA-protein.
A. A. Lapin, T. B. Kravchenko, A. N. Mokrievich, G. M. Vakhrameeva, T. I. Kombarova, I. A. Dyatlov, V. M. Pavlov   +6 more
doaj   +1 more source

Environmental adaptation of Francisella tularensis [PDF]

Microbes and Infection, 2009
Concerns over weaponizable bacteria have recently prompted considerable interest in Francisella tularensis (Ft). In addition to its potential illicit use, Ft occurs naturally in diverse ecological niches including mammals, arthropods, and fresh water protozoans.
Karsten R O, Hazlett, Kerry A, Cirillo
openaire   +2 more sources