Results 81 to 90 of about 21,361 (224)

Immunobiological Properties of Francisella tularensis Antigen Complexes

Проблемы особо опасных инфекций, 2011
Carried out are the studies of preparations of Francisella tularensis antigen complexes, obtained from the producer strains of different subspecies (holarctica, nearctica, mediasiatica, novicida).
E. M. Kuznetsova, O. A. Volokh, E. A. Smol`kova, T. N. Shchukovskaya, I. A. Shepelev, N. G. Avdeeva, A. L. Kravtsov, A. K. Nikiforov   +7 more
doaj   +1 more source

Francisella tularensis strain typing using multiple-locus, variable-number tandem repeat analysis [PDF]

, 2001
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisphere. After analyzing the F. tularensis genomic sequence for potential variable-number tandem repeats (VNTRs), we developed a multilocus VNTR analysis ...
Abrams, Michelle, Farlow, Jason, Keim, Paul, Lytle, Michael, Smith, Kimothy L., Wong, Jane   +5 more
core   +2 more sources

Functional characterization of Francisella tularensis subspecies holarctica genotypes during tick cell and macrophage infections using a proteogenomic approach

Frontiers in Cellular and Infection Microbiology
Tularemia is a vector-borne disease caused by the Gram-negative bacterium Francisella tularensis. Known hosts and vectors in Europe are hare and ticks. F.
Sara Doina Schütz, Sara Doina Schütz, Sara Doina Schütz, Maximilian Brackmann, Nicole Liechti, Michel Moser, Matthias Wittwer, Rémy Bruggmann   +7 more
doaj   +1 more source

Metapopulation structure for perpetuation of Francisella tularensis tularensis [PDF]

BMC Microbiology, 2009
AbstractBackgroundOutbreaks of Type A tularemia due toFrancisella tularensis tularensisare typically sporadic and unstable, greatly hindering identification of the determinants of perpetuation and human risk. Martha's Vineyard, Massachusetts has experienced an outbreak of Type A tularemia which has persisted for 9 years.
Telford Sam R, Saviet Benjamin, Goethert Heidi K   +2 more
openaire   +3 more sources

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Galleria mellonella Reveals Niche Differences Between Highly Pathogenic and Closely Related Strains of Francisella spp.

Frontiers in Cellular and Infection Microbiology, 2018
Francisella tularensis, a highly virulent bacteria that causes the zoonotic disease tularemia, is considered a potential agent of biological warfare and bioterrorism.
Johanna Thelaus, Eva Lundmark, Petter Lindgren, Andreas Sjödin, Mats Forsman   +4 more
doaj   +1 more source

Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Hélène Bouras, Yann Quesnelle, Suzanne Trancart, Didier Goux, Jean‐Louis Blin, Manuel Savary, Maryline Houssin, Céline Zatylny‐Gaudin   +7 more
wiley   +1 more source

First molecular detection of Francisella tularensis in turtle (Testudo graeca) and ticks (Hyalomma aegyptium) in Northwest of Iran

International Journal for Parasitology: Parasites and Wildlife
Francisella tularensis, causative agent of tularemia, is a contagious zoonotic ailment. This study was aimed to molecularly detect F. tularensis in tortoise blood (n = 100) and ticks (n = 100) collected in the West Azerbaijan province, Iran suing a ...
Amir Tukmechi, Abdulghaffar Ownagh, Ahmad Enferadi, Peyman Khademi   +3 more
doaj   +1 more source

Azithromycin effectiveness against intracellular infections of Francisella

BMC Microbiology, 2010
Background Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum ...
Mann Barbara J, Qin Aiping, Hunter Lyman, Ahmad Saira, van Hoek Monique L   +4 more
doaj   +1 more source

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection [PDF]

, 2016
Lysosomal cathepsins regulate an exquisite range of biological functions, and their deregulation is associated with inflammatory, metabolic, and degenerative diseases in humans.
Gurung, Prajwal, Guy, Clifford S, Kanneganti, Thirumala-Devi, Karki, Rajendra, Lamkanfi, Mohamed, Lupfer, Christopher, Malireddi, RK Subbarao, Man, Si Ming, Neale, Geoffrey, Qi, Xiaopeng   +9 more
core   +1 more source